Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic Cancer
Oxaliplatin is a new generation of platinum derivatives used frequently to treat solid organ malignancies, including colorectal and ovarian cancer. Recently, an oxaliplatin-based chemotherapeutic regimen was adopted for advanced pancreatic cancer. Although oxaliplatin has extensive therapeutic poten...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Jin Publishing & Printing Co.
2020-11-01
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| Series: | The Korean Journal of Gastroenterology |
| Subjects: | |
| Online Access: | http://www.kjg.or.kr/journal/view.html?uid=5644&vmd=Full |
| _version_ | 1818558246534774784 |
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| author | Sung Bum Kim So Yeong Kim Kook Hyun Kim Tae Nyeun Kim |
| author_facet | Sung Bum Kim So Yeong Kim Kook Hyun Kim Tae Nyeun Kim |
| author_sort | Sung Bum Kim |
| collection | DOAJ |
| description | Oxaliplatin is a new generation of platinum derivatives used frequently to treat solid organ malignancies, including colorectal and ovarian cancer. Recently, an oxaliplatin-based chemotherapeutic regimen was adopted for advanced pancreatic cancer. Although oxaliplatin has extensive therapeutic potential, its use can be limited by significant adverse effects, particularly ototoxicity. This paper reports a rare case of irreversible unilateral hearing loss in a 48-year-old female that developed after the intravenous infusion
of oxaliplatin during pancreatic cancer treatment. To the best of the authors’ knowledge, this is the second reported case of oxaliplatin-related ototoxicity in pancreatic cancer. |
| first_indexed | 2024-12-14T00:10:07Z |
| format | Article |
| id | doaj.art-ce5e7a8950bf4a5cb51295d9515f94b1 |
| institution | Directory Open Access Journal |
| issn | 1598-9992 2233-6869 |
| language | English |
| last_indexed | 2024-12-14T00:10:07Z |
| publishDate | 2020-11-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj.art-ce5e7a8950bf4a5cb51295d9515f94b12022-12-21T23:25:48ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692020-11-0176526126410.4166/kjg.2020.121Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic CancerSung Bum Kim0So Yeong Kim1Kook Hyun Kim2https://orcid.org/0000-0001-7786-7882Tae Nyeun Kim3Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, KoreaDepartment of Internal Medicine, Yeungnam University College of Medicine, Daegu, KoreaDepartment of Internal Medicine, Yeungnam University College of Medicine, Daegu, KoreaDepartment of Internal Medicine, Yeungnam University College of Medicine, Daegu, KoreaOxaliplatin is a new generation of platinum derivatives used frequently to treat solid organ malignancies, including colorectal and ovarian cancer. Recently, an oxaliplatin-based chemotherapeutic regimen was adopted for advanced pancreatic cancer. Although oxaliplatin has extensive therapeutic potential, its use can be limited by significant adverse effects, particularly ototoxicity. This paper reports a rare case of irreversible unilateral hearing loss in a 48-year-old female that developed after the intravenous infusion of oxaliplatin during pancreatic cancer treatment. To the best of the authors’ knowledge, this is the second reported case of oxaliplatin-related ototoxicity in pancreatic cancer.http://www.kjg.or.kr/journal/view.html?uid=5644&vmd=Fullototoxicityoxaliplatinchemotherapypancreatic neoplasms |
| spellingShingle | Sung Bum Kim So Yeong Kim Kook Hyun Kim Tae Nyeun Kim Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic Cancer The Korean Journal of Gastroenterology ototoxicity oxaliplatin chemotherapy pancreatic neoplasms |
| title | Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic Cancer |
| title_full | Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic Cancer |
| title_fullStr | Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic Cancer |
| title_full_unstemmed | Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic Cancer |
| title_short | Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic Cancer |
| title_sort | oxaliplatin induced sudden hearing loss in a patient with pancreatic cancer |
| topic | ototoxicity oxaliplatin chemotherapy pancreatic neoplasms |
| url | http://www.kjg.or.kr/journal/view.html?uid=5644&vmd=Full |
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