Regulating Androgen Receptor Function in Prostate Cancer: Exploring the Diversity of Post-Translational Modifications

Regulating Androgen Receptor Function in Prostate Cancer: Exploring the Diversity of Post-Translational Modifications

Androgen receptor (AR) transcriptional activity significantly influences prostate cancer (PCa) progression. In addition to ligand stimulation, AR transcriptional activity is also influenced by a variety of post-translational modifications (PTMs). A number of oncogenes and tumor suppressors have been...

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Bibliographic Details
Main Authors: Lance Edward V. Lumahan, Mazia Arif, Amy E. Whitener, Ping Yi
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cells
Subjects:
androgen receptor
post-translational modifications
prostate cancer
acetylation
methylation
phosphorylation
Online Access:https://www.mdpi.com/2073-4409/13/2/191

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