Treatment effect of mTOR-inhibition on tissue composition of renal angiomyolipomas in tuberous sclerosis complex (TSC).

Treatment effect of mTOR-inhibition on tissue composition of renal angiomyolipomas in tuberous sclerosis complex (TSC).

Tuberous sclerosis complex (TSC)-associated renal angiomyolipoma (AML) have a high lifetime risk of acute bleeding. MTOR-inhibitors are a promising novel treatment for TSC-AML, however adequate response to therapy can be difficult to assess. Early changes in MRI signal may serve as a novel early ind...

Full description

Bibliographic Details
Main Authors: Susanne Brakemeier, Lars Vogt, Lisa Adams, Bianca Zukunft, Gerd Diederichs, Bernd Hamm, Klemens Budde, Marcus R Makowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5726644?pdf=render

Internet

http://europepmc.org/articles/PMC5726644?pdf=render

Similar Items