Effects of perinatal complications on coagulation function in pregnant women

Objectives: To investigate the effects of various complications on the coagulation function of perinatal women. Methods: A total of 210 pregnant women between November 2016 and June 2017 were recruited. The coagulation function indexes, including prothrombin time (PT), activated partial thromboplast...

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Main Authors: Wei-Qin Yu, Xiao-Yan Liu, Pei-Min Mao
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2019-01-01
Series:Reproductive and Developmental Medicine
Subjects:
Online Access:http://www.repdevmed.org/article.asp?issn=2096-2924;year=2019;volume=3;issue=1;spage=60;epage=62;aulast=Yu
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author Wei-Qin Yu
Xiao-Yan Liu
Pei-Min Mao
author_facet Wei-Qin Yu
Xiao-Yan Liu
Pei-Min Mao
author_sort Wei-Qin Yu
collection DOAJ
description Objectives: To investigate the effects of various complications on the coagulation function of perinatal women. Methods: A total of 210 pregnant women between November 2016 and June 2017 were recruited. The coagulation function indexes, including prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB), and thrombin time (TT), were evaluated in pregnant women with group B Streptococcus (GBS), positive nonstress test (NST), scarred uterus, prenatal fever, macrosomia, gestational hypertension, gestational diabetes, premature rupture of membranes (PROMs), threatened abortion, and oligohydramnios. Results: No significant differences were found in PT, APTT, FIB, and TT in pregnant women with GBS, positive NST, scarred uterus, macrosomia, gestational hypertension, gestational diabetes, PROMs, and oligohydramnios. Moreover, significantly decreased PT and APTT and significantly increased TT were found in pregnant women with prenatal fever compared to normal controls, whereas significantly increased TT was also observed in those with threatened abortion. Conclusions: Among the complications that occur in pregnant women, prenatal fever and threatened abortion have important effects on coagulation function.
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spelling doaj.art-ce65c20095494655a7c9d541c54aceec2022-12-22T02:47:28ZengWolters Kluwer Health/LWWReproductive and Developmental Medicine2096-29242019-01-0131606210.4103/2096-2924.255989Effects of perinatal complications on coagulation function in pregnant womenWei-Qin YuXiao-Yan LiuPei-Min MaoObjectives: To investigate the effects of various complications on the coagulation function of perinatal women. Methods: A total of 210 pregnant women between November 2016 and June 2017 were recruited. The coagulation function indexes, including prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB), and thrombin time (TT), were evaluated in pregnant women with group B Streptococcus (GBS), positive nonstress test (NST), scarred uterus, prenatal fever, macrosomia, gestational hypertension, gestational diabetes, premature rupture of membranes (PROMs), threatened abortion, and oligohydramnios. Results: No significant differences were found in PT, APTT, FIB, and TT in pregnant women with GBS, positive NST, scarred uterus, macrosomia, gestational hypertension, gestational diabetes, PROMs, and oligohydramnios. Moreover, significantly decreased PT and APTT and significantly increased TT were found in pregnant women with prenatal fever compared to normal controls, whereas significantly increased TT was also observed in those with threatened abortion. Conclusions: Among the complications that occur in pregnant women, prenatal fever and threatened abortion have important effects on coagulation function.http://www.repdevmed.org/article.asp?issn=2096-2924;year=2019;volume=3;issue=1;spage=60;epage=62;aulast=YuCoagulation; Complication; Perinatal Period; Pregnancy; Prenatal Fever; Threatened Abortion
spellingShingle Wei-Qin Yu
Xiao-Yan Liu
Pei-Min Mao
Effects of perinatal complications on coagulation function in pregnant women
Reproductive and Developmental Medicine
Coagulation; Complication; Perinatal Period; Pregnancy; Prenatal Fever; Threatened Abortion
title Effects of perinatal complications on coagulation function in pregnant women
title_full Effects of perinatal complications on coagulation function in pregnant women
title_fullStr Effects of perinatal complications on coagulation function in pregnant women
title_full_unstemmed Effects of perinatal complications on coagulation function in pregnant women
title_short Effects of perinatal complications on coagulation function in pregnant women
title_sort effects of perinatal complications on coagulation function in pregnant women
topic Coagulation; Complication; Perinatal Period; Pregnancy; Prenatal Fever; Threatened Abortion
url http://www.repdevmed.org/article.asp?issn=2096-2924;year=2019;volume=3;issue=1;spage=60;epage=62;aulast=Yu
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