Soluble JAM-C Ectodomain Serves as the Niche for Adipose-Derived Stromal/Stem Cells

Soluble JAM-C Ectodomain Serves as the Niche for Adipose-Derived Stromal/Stem Cells

Junctional adhesion molecules (JAMs) are expressed in diverse types of stem and progenitor cells, but their physiological significance has yet to be established. Here, we report that JAMs exhibit a novel mode of interaction and biological activity in adipose-derived stromal/stem cells (ADSCs). Among...

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Bibliographic Details
Main Authors: Morio Yamazaki, Kotaro Sugimoto, Yo Mabuchi, Rina Yamashita, Naoki Ichikawa-Tomikawa, Tetsuharu Kaneko, Chihiro Akazawa, Hiroshi Hasegawa, Tetsuya Imura, Hideki Chiba
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomedicines
Subjects:
mesenchymal stem cell
stem cell
niche
junctional adhesion molecule
tight junction
shedding
Online Access:https://www.mdpi.com/2227-9059/9/3/278

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