Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand

Due to the fast, emerging development of antibiotic-resistant bacteria, the need for novel, efficient routes to battle these pathogens is crucial; in this scenario, metal-organic frameworks (MOFs) are promising materials for combating them effectively. Herein, a novel Cu-MOF—namely <b>1</b&...

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Main Authors: Estitxu Echenique-Errandonea, Sara Rojas, Víctor Karim Abdelkader-Fernández, Manuel Pérez-Mendoza, Ricardo F. Mendes, Paula Barbosa, Filipe Figueiredo, Flávio Figueira, Filipe A. Almeida Paz, José Manuel Delgado-López, Antonio Rodríguez-Diéguez, José Manuel Seco
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/22/8073
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author Estitxu Echenique-Errandonea
Sara Rojas
Víctor Karim Abdelkader-Fernández
Manuel Pérez-Mendoza
Ricardo F. Mendes
Paula Barbosa
Filipe Figueiredo
Flávio Figueira
Filipe A. Almeida Paz
José Manuel Delgado-López
Antonio Rodríguez-Diéguez
José Manuel Seco
author_facet Estitxu Echenique-Errandonea
Sara Rojas
Víctor Karim Abdelkader-Fernández
Manuel Pérez-Mendoza
Ricardo F. Mendes
Paula Barbosa
Filipe Figueiredo
Flávio Figueira
Filipe A. Almeida Paz
José Manuel Delgado-López
Antonio Rodríguez-Diéguez
José Manuel Seco
author_sort Estitxu Echenique-Errandonea
collection DOAJ
description Due to the fast, emerging development of antibiotic-resistant bacteria, the need for novel, efficient routes to battle these pathogens is crucial; in this scenario, metal-organic frameworks (MOFs) are promising materials for combating them effectively. Herein, a novel Cu-MOF—namely <b>1</b>—that displays the formula [Cu<sub>3</sub>L<sub>2</sub>(DMF)<sub>2</sub>]<sub>n</sub> (DMF = <i>N</i>,<i>N</i>-dimethylformamide) is described, synthesized by the combination of copper(II) and 3,4-dihydroxybenzoic acid (H<sub>3</sub>L)—both having well-known antibacterial properties. The resulting three-dimensional structure motivated us to study the antibacterial activity, adsorptive capacity and processability of the MOF in the form of pellets and membranes as a proof-of-concept to evaluate its future application in devices.
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spelling doaj.art-ce6c47d8dd6848fea6de41ee6af246362023-11-24T09:26:02ZengMDPI AGMolecules1420-30492022-11-012722807310.3390/molecules27228073Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate LigandEstitxu Echenique-Errandonea0Sara Rojas1Víctor Karim Abdelkader-Fernández2Manuel Pérez-Mendoza3Ricardo F. Mendes4Paula Barbosa5Filipe Figueiredo6Flávio Figueira7Filipe A. Almeida Paz8José Manuel Delgado-López9Antonio Rodríguez-Diéguez10José Manuel Seco11Departamento de Química Aplicada, Facultad de Química, Universidad del País Vasco UPV/EHU, Paseo Manuel Lardizabal, N° 3, 20018 Donostia-San Sebastián, SpainDepartamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, Av. Fuentenueva S/N, 18071 Granada, SpainDepartamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, Av. Fuentenueva S/N, 18071 Granada, SpainDepartamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, Av. Fuentenueva S/N, 18071 Granada, SpainDepartment of Chemistry, CICECO—Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Materials & Ceramic Engineering, CICECO—Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Materials & Ceramic Engineering, CICECO—Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Chemistry, CICECO—Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Chemistry, CICECO—Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, PortugalDepartamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, Av. Fuentenueva S/N, 18071 Granada, SpainDepartamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, Av. Fuentenueva S/N, 18071 Granada, SpainDepartamento de Química Aplicada, Facultad de Química, Universidad del País Vasco UPV/EHU, Paseo Manuel Lardizabal, N° 3, 20018 Donostia-San Sebastián, SpainDue to the fast, emerging development of antibiotic-resistant bacteria, the need for novel, efficient routes to battle these pathogens is crucial; in this scenario, metal-organic frameworks (MOFs) are promising materials for combating them effectively. Herein, a novel Cu-MOF—namely <b>1</b>—that displays the formula [Cu<sub>3</sub>L<sub>2</sub>(DMF)<sub>2</sub>]<sub>n</sub> (DMF = <i>N</i>,<i>N</i>-dimethylformamide) is described, synthesized by the combination of copper(II) and 3,4-dihydroxybenzoic acid (H<sub>3</sub>L)—both having well-known antibacterial properties. The resulting three-dimensional structure motivated us to study the antibacterial activity, adsorptive capacity and processability of the MOF in the form of pellets and membranes as a proof-of-concept to evaluate its future application in devices.https://www.mdpi.com/1420-3049/27/22/8073metal-organic frameworksmaterial processingadsorption capacityantibacterial activity
spellingShingle Estitxu Echenique-Errandonea
Sara Rojas
Víctor Karim Abdelkader-Fernández
Manuel Pérez-Mendoza
Ricardo F. Mendes
Paula Barbosa
Filipe Figueiredo
Flávio Figueira
Filipe A. Almeida Paz
José Manuel Delgado-López
Antonio Rodríguez-Diéguez
José Manuel Seco
Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand
Molecules
metal-organic frameworks
material processing
adsorption capacity
antibacterial activity
title Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand
title_full Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand
title_fullStr Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand
title_full_unstemmed Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand
title_short Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand
title_sort adsorptive capacity inhibitory activity and processing techniques for a copper mof based on the 3 4 dihydroxybenzoate ligand
topic metal-organic frameworks
material processing
adsorption capacity
antibacterial activity
url https://www.mdpi.com/1420-3049/27/22/8073
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