An Update on Multimodal Ophthalmological Imaging of Diffuse Choroidal Hemangioma in Sturge–Weber Syndrome
Sturge–Weber syndrome (SWS) is characterized by facial port-wine stains, leptomeningeal hemangiomas, and prominent ocular manifestations such as glaucoma and diffuse choroidal hemangiomas (DCHs). Imaging modalities are critical for diagnosing and longitudinally monitoring DCHs in SWS. Fundus photogr...
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| Format: | Article |
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MDPI AG
2023-10-01
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| Series: | Vision |
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| Online Access: | https://www.mdpi.com/2411-5150/7/4/64 |
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| author | Chiara Ciancimino Mariachiara Di Pippo Daria Rullo Francesco Ruggeri Flaminia Grassi Gianluca Scuderi Solmaz Abdolrahimzadeh |
| author_facet | Chiara Ciancimino Mariachiara Di Pippo Daria Rullo Francesco Ruggeri Flaminia Grassi Gianluca Scuderi Solmaz Abdolrahimzadeh |
| author_sort | Chiara Ciancimino |
| collection | DOAJ |
| description | Sturge–Weber syndrome (SWS) is characterized by facial port-wine stains, leptomeningeal hemangiomas, and prominent ocular manifestations such as glaucoma and diffuse choroidal hemangiomas (DCHs). Imaging modalities are critical for diagnosing and longitudinally monitoring DCHs in SWS. Fundus photography is fundamental in assessing both eyes simultaneously, fluorescein angiography and indocyanine green angiography effectively map the retinal and choroidal circulation, and ultrasonography offers essential structural insights into the choroid and retina. NIR imaging reveals subtle retinal pigment changes, often overlooked in standard fundus examination. Enhanced depth imaging spectral domain optical coherence tomography (EDI-SDOCT) and swept-source OCT (SSOCT) improve the visualization of the choroidal-scleral boundary, essential for DCH characterization. The potential of OCT angiography (OCTA) is under exploration, particularly its role in predicting signs of disease progression or worsening, as well as potential new biomarkers such as the choroidal vascularity index (CVI). The present review aims to provide an update on multimodal imaging of DCHs in SWS. |
| first_indexed | 2024-03-08T20:17:33Z |
| format | Article |
| id | doaj.art-ce6e4468521445fcadbfb04b3a820736 |
| institution | Directory Open Access Journal |
| issn | 2411-5150 |
| language | English |
| last_indexed | 2024-03-08T20:17:33Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vision |
| spelling | doaj.art-ce6e4468521445fcadbfb04b3a8207362023-12-22T14:49:32ZengMDPI AGVision2411-51502023-10-01746410.3390/vision7040064An Update on Multimodal Ophthalmological Imaging of Diffuse Choroidal Hemangioma in Sturge–Weber SyndromeChiara Ciancimino0Mariachiara Di Pippo1Daria Rullo2Francesco Ruggeri3Flaminia Grassi4Gianluca Scuderi5Solmaz Abdolrahimzadeh6Ophthalmology Unit, Neurosciences, Mental Health, and Sense Organs (@NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (@NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (@NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (@NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (@NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (@NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (@NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalySturge–Weber syndrome (SWS) is characterized by facial port-wine stains, leptomeningeal hemangiomas, and prominent ocular manifestations such as glaucoma and diffuse choroidal hemangiomas (DCHs). Imaging modalities are critical for diagnosing and longitudinally monitoring DCHs in SWS. Fundus photography is fundamental in assessing both eyes simultaneously, fluorescein angiography and indocyanine green angiography effectively map the retinal and choroidal circulation, and ultrasonography offers essential structural insights into the choroid and retina. NIR imaging reveals subtle retinal pigment changes, often overlooked in standard fundus examination. Enhanced depth imaging spectral domain optical coherence tomography (EDI-SDOCT) and swept-source OCT (SSOCT) improve the visualization of the choroidal-scleral boundary, essential for DCH characterization. The potential of OCT angiography (OCTA) is under exploration, particularly its role in predicting signs of disease progression or worsening, as well as potential new biomarkers such as the choroidal vascularity index (CVI). The present review aims to provide an update on multimodal imaging of DCHs in SWS.https://www.mdpi.com/2411-5150/7/4/64diffuse choroidal hemangiomaSturge–Weber syndromemultimodal imagingfundusenhanced depth imagingspectral domain optical coherence tomography (OCT) |
| spellingShingle | Chiara Ciancimino Mariachiara Di Pippo Daria Rullo Francesco Ruggeri Flaminia Grassi Gianluca Scuderi Solmaz Abdolrahimzadeh An Update on Multimodal Ophthalmological Imaging of Diffuse Choroidal Hemangioma in Sturge–Weber Syndrome Vision diffuse choroidal hemangioma Sturge–Weber syndrome multimodal imaging fundus enhanced depth imaging spectral domain optical coherence tomography (OCT) |
| title | An Update on Multimodal Ophthalmological Imaging of Diffuse Choroidal Hemangioma in Sturge–Weber Syndrome |
| title_full | An Update on Multimodal Ophthalmological Imaging of Diffuse Choroidal Hemangioma in Sturge–Weber Syndrome |
| title_fullStr | An Update on Multimodal Ophthalmological Imaging of Diffuse Choroidal Hemangioma in Sturge–Weber Syndrome |
| title_full_unstemmed | An Update on Multimodal Ophthalmological Imaging of Diffuse Choroidal Hemangioma in Sturge–Weber Syndrome |
| title_short | An Update on Multimodal Ophthalmological Imaging of Diffuse Choroidal Hemangioma in Sturge–Weber Syndrome |
| title_sort | update on multimodal ophthalmological imaging of diffuse choroidal hemangioma in sturge weber syndrome |
| topic | diffuse choroidal hemangioma Sturge–Weber syndrome multimodal imaging fundus enhanced depth imaging spectral domain optical coherence tomography (OCT) |
| url | https://www.mdpi.com/2411-5150/7/4/64 |
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