Molecular and immunohistochemical study of APC exon 16 and its possible role in colorectal carcinoma development

Molecular and immunohistochemical study of APC exon 16 and its possible role in colorectal carcinoma development

Background: Colorectal cancer ranks second as a cause of cancer deaths. Mutations in the adenomatous polyposis coli (APC) gene, especially in exon 16, could contribute to colorectal carcinoma development. This study explored the correlations between APC gene exon 16 variations/expression and colorec...

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Bibliographic Details
Main Authors: Hamid K. Al-Tameemi, Rand M. Al-Husseini, Rihab H. Al-Mudhafer, Hussein A. Abid, Hussein Raof Al-Gazali, Dina A.A. Abdullah, Mustafa T. Albaldawy
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Carcinogenesis
Colorectal neoplasms
Exons
Human APC protein
Immunohistochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023106517

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