Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study

BackgroundWhether there is an association between TFAs and periodontitis is unclear. The purpose of this study was to investigate the relationship between moderate/severe periodontitis and plasma level of elaidic acid, a major trans-fatty acid component, in American adults.MethodsThe National Health...

Full description

Bibliographic Details
Main Authors: Hu Jiaxin, Chen Zhu, Yang Jing, Shi Qianhui, Jin Fuqian, Pang Qiyuan, Luo Yi, Song Jukun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.1034841/full
_version_ 1811205915113684992
author Hu Jiaxin
Hu Jiaxin
Chen Zhu
Yang Jing
Shi Qianhui
Jin Fuqian
Jin Fuqian
Pang Qiyuan
Luo Yi
Luo Yi
Song Jukun
author_facet Hu Jiaxin
Hu Jiaxin
Chen Zhu
Yang Jing
Shi Qianhui
Jin Fuqian
Jin Fuqian
Pang Qiyuan
Luo Yi
Luo Yi
Song Jukun
author_sort Hu Jiaxin
collection DOAJ
description BackgroundWhether there is an association between TFAs and periodontitis is unclear. The purpose of this study was to investigate the relationship between moderate/severe periodontitis and plasma level of elaidic acid, a major trans-fatty acid component, in American adults.MethodsThe National Health and Nutrition Examination Survey (NHANES) years 2009–2010 were used to screen a total of 1,610 people. The independent variable of interest is plasma elaidic acid level, the dependent variable is periodontitis, and the covariates include socio-demographic variables, lifestyle variables, systemic diseases, etc. The distribution of variables in the covariate differences between the different independent groups according to tertile was investigated using a multiple linear regression model. To examine the association between plasma elaidic acid levels and moderate/severe periodontitis, three models were used.ResultsMultiple logistic regression analysis showed a significant association between plasma elaidic acid level and moderate/severe periodontitis after adjustment for potential confounders (OR = 1.021, 95%CI: 1.004–1.039, P = 0.01394). Subjects with the highest tertile of plasma elaidic acid levels were 51.9% more likely to have periodontitis compared with subjects with the lowest tertile of plasma elaidic acid levels (OR = 1.519, 95% CI: 1.136–2.030, P = 0.00477). No possible sources of heterogeneity were identified in the subgroup analyses.ConclusionPlasma elaidic acid levels are associated with periodontal disease in American adults.
first_indexed 2024-04-12T03:39:18Z
format Article
id doaj.art-ce71deda85934b30a3a782c1b3a83fbd
institution Directory Open Access Journal
issn 2296-861X
language English
last_indexed 2024-04-12T03:39:18Z
publishDate 2022-12-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Nutrition
spelling doaj.art-ce71deda85934b30a3a782c1b3a83fbd2022-12-22T03:49:20ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-12-01910.3389/fnut.2022.10348411034841Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional studyHu Jiaxin0Hu Jiaxin1Chen Zhu2Yang Jing3Shi Qianhui4Jin Fuqian5Jin Fuqian6Pang Qiyuan7Luo Yi8Luo Yi9Song Jukun10Guiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, ChinaThe Affiliated Stomatological Hospital and Stomatology of Guizhou Medical University, Guizhou Medical University, Guiyang, ChinaBackgroundWhether there is an association between TFAs and periodontitis is unclear. The purpose of this study was to investigate the relationship between moderate/severe periodontitis and plasma level of elaidic acid, a major trans-fatty acid component, in American adults.MethodsThe National Health and Nutrition Examination Survey (NHANES) years 2009–2010 were used to screen a total of 1,610 people. The independent variable of interest is plasma elaidic acid level, the dependent variable is periodontitis, and the covariates include socio-demographic variables, lifestyle variables, systemic diseases, etc. The distribution of variables in the covariate differences between the different independent groups according to tertile was investigated using a multiple linear regression model. To examine the association between plasma elaidic acid levels and moderate/severe periodontitis, three models were used.ResultsMultiple logistic regression analysis showed a significant association between plasma elaidic acid level and moderate/severe periodontitis after adjustment for potential confounders (OR = 1.021, 95%CI: 1.004–1.039, P = 0.01394). Subjects with the highest tertile of plasma elaidic acid levels were 51.9% more likely to have periodontitis compared with subjects with the lowest tertile of plasma elaidic acid levels (OR = 1.519, 95% CI: 1.136–2.030, P = 0.00477). No possible sources of heterogeneity were identified in the subgroup analyses.ConclusionPlasma elaidic acid levels are associated with periodontal disease in American adults.https://www.frontiersin.org/articles/10.3389/fnut.2022.1034841/fullNHANESinflammationperiodontal healthtrans fatty acidselaidic acidtrans-9-octadecenoic acid
spellingShingle Hu Jiaxin
Hu Jiaxin
Chen Zhu
Yang Jing
Shi Qianhui
Jin Fuqian
Jin Fuqian
Pang Qiyuan
Luo Yi
Luo Yi
Song Jukun
Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study
Frontiers in Nutrition
NHANES
inflammation
periodontal health
trans fatty acids
elaidic acid
trans-9-octadecenoic acid
title Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study
title_full Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study
title_fullStr Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study
title_full_unstemmed Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study
title_short Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study
title_sort plasma elaidic acid level is associated with periodontal health in american adults a cross sectional study
topic NHANES
inflammation
periodontal health
trans fatty acids
elaidic acid
trans-9-octadecenoic acid
url https://www.frontiersin.org/articles/10.3389/fnut.2022.1034841/full
work_keys_str_mv AT hujiaxin plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT hujiaxin plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT chenzhu plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT yangjing plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT shiqianhui plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT jinfuqian plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT jinfuqian plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT pangqiyuan plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT luoyi plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT luoyi plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy
AT songjukun plasmaelaidicacidlevelisassociatedwithperiodontalhealthinamericanadultsacrosssectionalstudy