Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study
BackgroundWhether there is an association between TFAs and periodontitis is unclear. The purpose of this study was to investigate the relationship between moderate/severe periodontitis and plasma level of elaidic acid, a major trans-fatty acid component, in American adults.MethodsThe National Health...
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Frontiers Media S.A.
2022-12-01
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Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.1034841/full |
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author | Hu Jiaxin Hu Jiaxin Chen Zhu Yang Jing Shi Qianhui Jin Fuqian Jin Fuqian Pang Qiyuan Luo Yi Luo Yi Song Jukun |
author_facet | Hu Jiaxin Hu Jiaxin Chen Zhu Yang Jing Shi Qianhui Jin Fuqian Jin Fuqian Pang Qiyuan Luo Yi Luo Yi Song Jukun |
author_sort | Hu Jiaxin |
collection | DOAJ |
description | BackgroundWhether there is an association between TFAs and periodontitis is unclear. The purpose of this study was to investigate the relationship between moderate/severe periodontitis and plasma level of elaidic acid, a major trans-fatty acid component, in American adults.MethodsThe National Health and Nutrition Examination Survey (NHANES) years 2009–2010 were used to screen a total of 1,610 people. The independent variable of interest is plasma elaidic acid level, the dependent variable is periodontitis, and the covariates include socio-demographic variables, lifestyle variables, systemic diseases, etc. The distribution of variables in the covariate differences between the different independent groups according to tertile was investigated using a multiple linear regression model. To examine the association between plasma elaidic acid levels and moderate/severe periodontitis, three models were used.ResultsMultiple logistic regression analysis showed a significant association between plasma elaidic acid level and moderate/severe periodontitis after adjustment for potential confounders (OR = 1.021, 95%CI: 1.004–1.039, P = 0.01394). Subjects with the highest tertile of plasma elaidic acid levels were 51.9% more likely to have periodontitis compared with subjects with the lowest tertile of plasma elaidic acid levels (OR = 1.519, 95% CI: 1.136–2.030, P = 0.00477). No possible sources of heterogeneity were identified in the subgroup analyses.ConclusionPlasma elaidic acid levels are associated with periodontal disease in American adults. |
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spelling | doaj.art-ce71deda85934b30a3a782c1b3a83fbd2022-12-22T03:49:20ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-12-01910.3389/fnut.2022.10348411034841Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional studyHu Jiaxin0Hu Jiaxin1Chen Zhu2Yang Jing3Shi Qianhui4Jin Fuqian5Jin Fuqian6Pang Qiyuan7Luo Yi8Luo Yi9Song Jukun10Guiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaGuiyang Hospital of Stomatology, Guiyang, Guizhou, ChinaSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, ChinaThe Affiliated Stomatological Hospital and Stomatology of Guizhou Medical University, Guizhou Medical University, Guiyang, ChinaBackgroundWhether there is an association between TFAs and periodontitis is unclear. The purpose of this study was to investigate the relationship between moderate/severe periodontitis and plasma level of elaidic acid, a major trans-fatty acid component, in American adults.MethodsThe National Health and Nutrition Examination Survey (NHANES) years 2009–2010 were used to screen a total of 1,610 people. The independent variable of interest is plasma elaidic acid level, the dependent variable is periodontitis, and the covariates include socio-demographic variables, lifestyle variables, systemic diseases, etc. The distribution of variables in the covariate differences between the different independent groups according to tertile was investigated using a multiple linear regression model. To examine the association between plasma elaidic acid levels and moderate/severe periodontitis, three models were used.ResultsMultiple logistic regression analysis showed a significant association between plasma elaidic acid level and moderate/severe periodontitis after adjustment for potential confounders (OR = 1.021, 95%CI: 1.004–1.039, P = 0.01394). Subjects with the highest tertile of plasma elaidic acid levels were 51.9% more likely to have periodontitis compared with subjects with the lowest tertile of plasma elaidic acid levels (OR = 1.519, 95% CI: 1.136–2.030, P = 0.00477). No possible sources of heterogeneity were identified in the subgroup analyses.ConclusionPlasma elaidic acid levels are associated with periodontal disease in American adults.https://www.frontiersin.org/articles/10.3389/fnut.2022.1034841/fullNHANESinflammationperiodontal healthtrans fatty acidselaidic acidtrans-9-octadecenoic acid |
spellingShingle | Hu Jiaxin Hu Jiaxin Chen Zhu Yang Jing Shi Qianhui Jin Fuqian Jin Fuqian Pang Qiyuan Luo Yi Luo Yi Song Jukun Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study Frontiers in Nutrition NHANES inflammation periodontal health trans fatty acids elaidic acid trans-9-octadecenoic acid |
title | Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study |
title_full | Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study |
title_fullStr | Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study |
title_full_unstemmed | Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study |
title_short | Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study |
title_sort | plasma elaidic acid level is associated with periodontal health in american adults a cross sectional study |
topic | NHANES inflammation periodontal health trans fatty acids elaidic acid trans-9-octadecenoic acid |
url | https://www.frontiersin.org/articles/10.3389/fnut.2022.1034841/full |
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