Oral and Laryngeal Diadochokinetic Rate in Multiple Sclerosis: Relationship to Disease Progression
Background: The first purpose of this study was to investigate the rate of oral and laryngeal Diadochokinesis (DDK) in Multiple Sclerosis (MS) patients in comparison with healthy people. The second goal was to determine if DDK rate has any relationship with the disease progression.Methods: In this c...
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| Format: | Article |
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Kerman University of Medical Sciences
2018-03-01
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| Series: | Journal of Kerman University of Medical Sciences |
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| Online Access: | https://jkmu.kmu.ac.ir/article_66885_1a9a3243c35d2af8784ad8ae9ef70723.pdf |
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| author | Sepideh Ansari Majid Soltani Negin Moradi Hossein Rezai Latifi Seyed Mahmoud Nastaran Majdinasab |
| author_facet | Sepideh Ansari Majid Soltani Negin Moradi Hossein Rezai Latifi Seyed Mahmoud Nastaran Majdinasab |
| author_sort | Sepideh Ansari |
| collection | DOAJ |
| description | Background: The first purpose of this study was to investigate the rate of oral and laryngeal Diadochokinesis (DDK) in Multiple Sclerosis (MS) patients in comparison with healthy people. The second goal was to determine if DDK rate has any relationship with the disease progression.Methods: In this cross-sectional study, two groups were enrolled: MS patients (n=31) and healthy subjects (n=14) . The samples of DDK tasks were collected. The scores of Expanded Disability Status Scale (EDSS) and duration of disease were considered as the indices of disease progression.Results: There were significant differences between the two groups in the rates of all DDK tasks (P≤0.001). Significant correlations were found between laryngeal DDK tasks and disease progression (r = - 0.488, r = -0.396, r = -0.444, r = - 0.667, P ≤ 0.027). Two oral DDK tasks were in correlation with EDSS and the disease duration (r = -0.403, r = -0.446, r =-0.521, r = -0.465, p≤0.025). There were high correlations between functional systems of EDSS (pyramidal, cerebellar and brainstem) and DDK tasks (r = - 0.448, r = -452, r = -0.458, r =-0.379, P ≤ 0.036).Conclusions: In the present study, poor performance in DDK tasks provided evidence for insufficient motor control over related speech subsystems in MS. These findings suggest that DDK rate is a sensitive beneficial speech motor control assessment in MS. Moreover, DDK tasks might be introduced as additional prognostic parameters for detecting disease progression and evaluating treatment achievements. |
| first_indexed | 2024-03-13T02:08:31Z |
| format | Article |
| id | doaj.art-ce744458a34046d59ba0f55c1bd823a4 |
| institution | Directory Open Access Journal |
| issn | 2008-2843 |
| language | English |
| last_indexed | 2024-03-13T02:08:31Z |
| publishDate | 2018-03-01 |
| publisher | Kerman University of Medical Sciences |
| record_format | Article |
| series | Journal of Kerman University of Medical Sciences |
| spelling | doaj.art-ce744458a34046d59ba0f55c1bd823a42023-07-01T05:17:19ZengKerman University of Medical SciencesJournal of Kerman University of Medical Sciences2008-28432018-03-0125216417466885Oral and Laryngeal Diadochokinetic Rate in Multiple Sclerosis: Relationship to Disease ProgressionSepideh Ansari0Majid Soltani1Negin Moradi2Hossein Rezai3Latifi Seyed Mahmoud4Nastaran Majdinasab5Musculoskeletal Rehabilitation Research Center, Speech Therapy Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranAssistant Professor, Musculoskeletal Rehabilitation Research Center, Speech Therapy Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranAssistant Professor, Musculoskeletal Rehabilitation Research Center, Speech Therapy Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranUniversity Lecturer, Musculoskeletal Rehabilitation Research Center, Speech Therapy Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranHealth Research Institute, Diabetes Research center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranAssistant Professor, Department of Neurology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranBackground: The first purpose of this study was to investigate the rate of oral and laryngeal Diadochokinesis (DDK) in Multiple Sclerosis (MS) patients in comparison with healthy people. The second goal was to determine if DDK rate has any relationship with the disease progression.Methods: In this cross-sectional study, two groups were enrolled: MS patients (n=31) and healthy subjects (n=14) . The samples of DDK tasks were collected. The scores of Expanded Disability Status Scale (EDSS) and duration of disease were considered as the indices of disease progression.Results: There were significant differences between the two groups in the rates of all DDK tasks (P≤0.001). Significant correlations were found between laryngeal DDK tasks and disease progression (r = - 0.488, r = -0.396, r = -0.444, r = - 0.667, P ≤ 0.027). Two oral DDK tasks were in correlation with EDSS and the disease duration (r = -0.403, r = -0.446, r =-0.521, r = -0.465, p≤0.025). There were high correlations between functional systems of EDSS (pyramidal, cerebellar and brainstem) and DDK tasks (r = - 0.448, r = -452, r = -0.458, r =-0.379, P ≤ 0.036).Conclusions: In the present study, poor performance in DDK tasks provided evidence for insufficient motor control over related speech subsystems in MS. These findings suggest that DDK rate is a sensitive beneficial speech motor control assessment in MS. Moreover, DDK tasks might be introduced as additional prognostic parameters for detecting disease progression and evaluating treatment achievements.https://jkmu.kmu.ac.ir/article_66885_1a9a3243c35d2af8784ad8ae9ef70723.pdfspeech motor controlmultiple sclerosisdiadochokinesis |
| spellingShingle | Sepideh Ansari Majid Soltani Negin Moradi Hossein Rezai Latifi Seyed Mahmoud Nastaran Majdinasab Oral and Laryngeal Diadochokinetic Rate in Multiple Sclerosis: Relationship to Disease Progression Journal of Kerman University of Medical Sciences speech motor control multiple sclerosis diadochokinesis |
| title | Oral and Laryngeal Diadochokinetic Rate in Multiple Sclerosis: Relationship to Disease Progression |
| title_full | Oral and Laryngeal Diadochokinetic Rate in Multiple Sclerosis: Relationship to Disease Progression |
| title_fullStr | Oral and Laryngeal Diadochokinetic Rate in Multiple Sclerosis: Relationship to Disease Progression |
| title_full_unstemmed | Oral and Laryngeal Diadochokinetic Rate in Multiple Sclerosis: Relationship to Disease Progression |
| title_short | Oral and Laryngeal Diadochokinetic Rate in Multiple Sclerosis: Relationship to Disease Progression |
| title_sort | oral and laryngeal diadochokinetic rate in multiple sclerosis relationship to disease progression |
| topic | speech motor control multiple sclerosis diadochokinesis |
| url | https://jkmu.kmu.ac.ir/article_66885_1a9a3243c35d2af8784ad8ae9ef70723.pdf |
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