Comprehensive ex vivo and in vivo preclinical evaluation of novel chemo enzymatic decellularized peripheral nerve allografts

Comprehensive ex vivo and in vivo preclinical evaluation of novel chemo enzymatic decellularized peripheral nerve allografts

As a reliable alternative to autografts, decellularized peripheral nerve allografts (DPNAs) should mimic the complex microstructure of native nerves and be immunogenically compatible. Nevertheless, there is a current lack of decellularization methods able to remove peripheral nerve cells without sig...

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Bibliographic Details
Main Authors: Óscar Darío García-García, Marwa El Soury, Fernando Campos, David Sánchez-Porras, Stefano Geuna, Miguel Alaminos, Giovanna Gambarotta, Jesús Chato-Astrain, Stefania Raimondo, Víctor Carriel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
acellular graft
decellularization
decellularized nerve allograft
peripheral nerve repair
tissue engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1162684/full

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