No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks’ Outcome?
The national reference network NETSARC+ provides remote access to specialized diagnosis and the Multidisciplinary Tumour Board (MTB) to improve the management and survival of sarcoma patients in France. The IGéAS research program aims to assess the potential of this innovative organization to addres...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/11/2620 |
| _version_ | 1797494007848239104 |
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| author | Yohan Fayet Christine Chevreau Gauthier Decanter Cécile Dalban Pierre Meeus Sébastien Carrère Leila Haddag-Miliani François Le Loarer Sylvain Causeret Daniel Orbach Michelle Kind Louis-Romée Le Nail Gwenaël Ferron Hélène Labrosse Loïc Chaigneau François Bertucci Jean-Christophe Ruzic Valérie Le Brun Ly Fadila Farsi Emmanuelle Bompas Sabine Noal Aurore Vozy Agnes Ducoulombier Clément Bonnet Sylvie Chabaud Françoise Ducimetière Camille Tlemsani Mickaël Ropars Olivier Collard Paul Michelin Justine Gantzer Pascale Dubray-Longeras Maria Rios Pauline Soibinet Axel Le Cesne Florence Duffaud Marie Karanian François Gouin Raphaël Tétreau Charles Honoré Jean-Michel Coindre Isabelle Ray-Coquard Sylvie Bonvalot Jean-Yves Blay |
| author_facet | Yohan Fayet Christine Chevreau Gauthier Decanter Cécile Dalban Pierre Meeus Sébastien Carrère Leila Haddag-Miliani François Le Loarer Sylvain Causeret Daniel Orbach Michelle Kind Louis-Romée Le Nail Gwenaël Ferron Hélène Labrosse Loïc Chaigneau François Bertucci Jean-Christophe Ruzic Valérie Le Brun Ly Fadila Farsi Emmanuelle Bompas Sabine Noal Aurore Vozy Agnes Ducoulombier Clément Bonnet Sylvie Chabaud Françoise Ducimetière Camille Tlemsani Mickaël Ropars Olivier Collard Paul Michelin Justine Gantzer Pascale Dubray-Longeras Maria Rios Pauline Soibinet Axel Le Cesne Florence Duffaud Marie Karanian François Gouin Raphaël Tétreau Charles Honoré Jean-Michel Coindre Isabelle Ray-Coquard Sylvie Bonvalot Jean-Yves Blay |
| author_sort | Yohan Fayet |
| collection | DOAJ |
| description | The national reference network NETSARC+ provides remote access to specialized diagnosis and the Multidisciplinary Tumour Board (MTB) to improve the management and survival of sarcoma patients in France. The IGéAS research program aims to assess the potential of this innovative organization to address geographical inequalities in cancer management. Using the IGéAS cohort built from the nationwide NETSARC+ database, the individual, clinical, and geographical determinants of the 3-year overall survival of sarcoma patients in France were analyzed. The survival analysis was focused on patients diagnosed in 2013 (n = 2281) to ensure sufficient hindsight to collect patient follow-up. Our study included patients with bone (16.8%), soft-tissue (69%), and visceral (14.2%) sarcomas, with a median age of 61.8 years. The overall survival was not associated with geographical variables after adjustment for individual and clinical factors. The lower survival in precarious population districts [HR 1.23, 95% CI 1.02 to 1.48] in comparison to wealthy metropolitan areas (HR = 1) found in univariable analysis was due to the worst clinical presentation at diagnosis of patients. The place of residence had no impact on sarcoma patients’ survival, in the context of the national organization driven by the reference network. Following previous findings, this suggests the ability of this organization to go through geographical barriers usually impeding the optimal management of cancer patients. |
| first_indexed | 2024-03-10T01:28:07Z |
| format | Article |
| id | doaj.art-ce7678ed718e42f987c0a33721185cb6 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T01:28:07Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-ce7678ed718e42f987c0a33721185cb62023-11-23T13:48:19ZengMDPI AGCancers2072-66942022-05-011411262010.3390/cancers14112620No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks’ Outcome?Yohan Fayet0Christine Chevreau1Gauthier Decanter2Cécile Dalban3Pierre Meeus4Sébastien Carrère5Leila Haddag-Miliani6François Le Loarer7Sylvain Causeret8Daniel Orbach9Michelle Kind10Louis-Romée Le Nail11Gwenaël Ferron12Hélène Labrosse13Loïc Chaigneau14François Bertucci15Jean-Christophe Ruzic16Valérie Le Brun Ly17Fadila Farsi18Emmanuelle Bompas19Sabine Noal20Aurore Vozy21Agnes Ducoulombier22Clément Bonnet23Sylvie Chabaud24Françoise Ducimetière25Camille Tlemsani26Mickaël Ropars27Olivier Collard28Paul Michelin29Justine Gantzer30Pascale Dubray-Longeras31Maria Rios32Pauline Soibinet33Axel Le Cesne34Florence Duffaud35Marie Karanian36François Gouin37Raphaël Tétreau38Charles Honoré39Jean-Michel Coindre40Isabelle Ray-Coquard41Sylvie Bonvalot42Jean-Yves Blay43EMS Team–Human and Social Sciences Department, Centre Léon Bérard, 69008 Lyon, FranceICR IUCT-Oncopole, 31000 Toulouse, FranceDepartment of Surgical Oncology, Oscar Lambret Center, 59000 Lille, FranceDepartment of Clinical Research and Innovation, Centre Léon Bérard, 69008 Lyon, FranceDepartment of Surgery, Centre Léon Bérard, 69008 Lyon, FranceInstitut de Recherche en Cancérologie Montpellier, INSERM U1194, 34000 Montpellier, FranceService D’imagerie Diagnostique, Institut Gustave Roussy, 94800 Villejuif, FranceDepartment of Pathology, Institut Bergonié, 33000 Bordeaux, FranceCentre Georges François Leclerc, 21000 Dijon, FranceCentre Oncologie SIREDO (Soins, Innovation et Recherche en Oncologie de l’Enfant, de l’aDOlescents et de L’adulte Jeune), Institut Curie, Université de Recherche Paris Sciences et Lettres, 75005 Paris, FranceRadiologue, Département D’imagerie Médicale, Institut Bergonié, 33000 Bordeaux, FranceDepartment of Orthopaedic Surgery, CHU de Tours, Faculté de Médecine, Université de Tours, 37000 Tours, FranceINSERM CRCT19 ONCO-SARC (Sarcoma Oncogenesis), Institut Claudius Regaud-Institut Universitaire du Cancer, 31000 Toulouse, FranceCRLCC Léon Berard, Oncology Regional Network ONCO-AURA, 69008 Lyon, FranceDepartment of Medical Oncology, CHRU Jean Minjoz, 25000 Besançon, FranceDepartment of Medical Oncology, Institut Paoli-Calmettes, 13009 Marseille, FranceCHU Réunion, 97410 Saint-Pierre, FranceService D’oncologie Médicale, CHU Dupuytren, 87000 Limoges, FranceCRLCC Léon Berard, Oncology Regional Network ONCO-AURA, 69008 Lyon, FranceMedical Oncology Department, ICO, 44800 Saint Herblain, FranceUCP Sarcome, Centre François Baclesse, 14000 Caen, FranceDepartment of Medical Oncology, Pitié Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Institut Universitaire de Cancérologie (IUC), CLIP(2) Galilée, Sorbonne University, 75013 Paris, FranceCentre Antoine-Lacassagne, 06000 Nice, FranceService d’Oncologie Médicale Hôpital Saint Louis, 75010 Paris, FranceDepartment of Clinical Research and Innovation, Centre Léon Bérard, 69008 Lyon, FranceEquipe EMS, Centre Léon Bérard, 69008 Lyon, FranceService d’Oncologie Médicale, Hôpital Cochin, Institut du Cancer Paris CARPEM, Université de Paris, APHP Centre, 75014 Paris, FranceOrthopaedic and Trauma Department, Pontchaillou University Hospital, University of Rennes 1, 35000 Rennes, FranceDépartement d’Oncologie Médicale, Hôpital Privé de la Loire, 42100 Saint-Etienne, FranceService D’imagerie Médicale, CHU Hopitaux de Rouen-Hopital Charles Nicolle, 76000 Rouen, FranceDepartment of Medical Oncology, Strasbourg-Europe Cancer Institute (ICANS), 67033 Strasbourg, FranceOncology Department, Centre Jean Perrin, 63011 Clermont-Ferrand, FranceDepartment of Medical Oncology, Cancer Institute of Lorraine-Alexis Vautrin, 54500 Vandoeuvre Les Nancy, FranceDepartment of Hepato-Gastroenterology and Digestive Oncology, Reims University Hospital, 51000 Reims, FranceMedical Oncology, Insitut Gustave Roussy, 94800 Villejuif, FranceDepartment of Medical Oncology, CHU La Timone and Aix-Marseille Université (AMU), 13005 Marseille, FranceDepartment of Pathology, Lyon University Hospital, 69008 Lyon, FranceDepartment of Surgery, Centre Léon Bérard, 69008 Lyon, FranceMedical Imaging Center, Institut du Cancer, 34000 Montpellier, FranceDepartment of Surgical Oncology, Gustave Roussy, Villejuif 94800, FranceDepartment of Pathology, Institut Bergonié, 33000 Bordeaux, FranceDepartment of Medical Oncology, Centre Leon Berard, 69008 Lyon, FranceDepartment of Surgical Oncology, Institut Curie, Université Paris Sciences et Lettres, 75005 Paris, FranceDepartment of Medical Oncology, Centre Léon Bérard, Lyon University, 69008 Lyon, FranceThe national reference network NETSARC+ provides remote access to specialized diagnosis and the Multidisciplinary Tumour Board (MTB) to improve the management and survival of sarcoma patients in France. The IGéAS research program aims to assess the potential of this innovative organization to address geographical inequalities in cancer management. Using the IGéAS cohort built from the nationwide NETSARC+ database, the individual, clinical, and geographical determinants of the 3-year overall survival of sarcoma patients in France were analyzed. The survival analysis was focused on patients diagnosed in 2013 (n = 2281) to ensure sufficient hindsight to collect patient follow-up. Our study included patients with bone (16.8%), soft-tissue (69%), and visceral (14.2%) sarcomas, with a median age of 61.8 years. The overall survival was not associated with geographical variables after adjustment for individual and clinical factors. The lower survival in precarious population districts [HR 1.23, 95% CI 1.02 to 1.48] in comparison to wealthy metropolitan areas (HR = 1) found in univariable analysis was due to the worst clinical presentation at diagnosis of patients. The place of residence had no impact on sarcoma patients’ survival, in the context of the national organization driven by the reference network. Following previous findings, this suggests the ability of this organization to go through geographical barriers usually impeding the optimal management of cancer patients.https://www.mdpi.com/2072-6694/14/11/2620spatial inequalitiesreference networksremotenesssocial deprivationrare cancersFrance |
| spellingShingle | Yohan Fayet Christine Chevreau Gauthier Decanter Cécile Dalban Pierre Meeus Sébastien Carrère Leila Haddag-Miliani François Le Loarer Sylvain Causeret Daniel Orbach Michelle Kind Louis-Romée Le Nail Gwenaël Ferron Hélène Labrosse Loïc Chaigneau François Bertucci Jean-Christophe Ruzic Valérie Le Brun Ly Fadila Farsi Emmanuelle Bompas Sabine Noal Aurore Vozy Agnes Ducoulombier Clément Bonnet Sylvie Chabaud Françoise Ducimetière Camille Tlemsani Mickaël Ropars Olivier Collard Paul Michelin Justine Gantzer Pascale Dubray-Longeras Maria Rios Pauline Soibinet Axel Le Cesne Florence Duffaud Marie Karanian François Gouin Raphaël Tétreau Charles Honoré Jean-Michel Coindre Isabelle Ray-Coquard Sylvie Bonvalot Jean-Yves Blay No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks’ Outcome? Cancers spatial inequalities reference networks remoteness social deprivation rare cancers France |
| title | No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks’ Outcome? |
| title_full | No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks’ Outcome? |
| title_fullStr | No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks’ Outcome? |
| title_full_unstemmed | No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks’ Outcome? |
| title_short | No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks’ Outcome? |
| title_sort | no geographical inequalities in survival for sarcoma patients in france a reference networks outcome |
| topic | spatial inequalities reference networks remoteness social deprivation rare cancers France |
| url | https://www.mdpi.com/2072-6694/14/11/2620 |
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