Coordinated Evolution of Influenza A Surface Proteins.

Coordinated Evolution of Influenza A Surface Proteins.

The surface proteins hemagglutinin (HA) and neuraminidase (NA) of human influenza A virus evolve under selection pressures to escape adaptive immune responses and antiviral drug treatments. In addition to these external selection pressures, some mutations in HA are known to affect the adaptive lands...

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Bibliographic Details
Main Authors:	Alexey D Neverov, Sergey Kryazhimskiy, Joshua B Plotkin, Georgii A Bazykin
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-08-01
Series:	PLoS Genetics
Online Access:	http://europepmc.org/articles/PMC4527594?pdf=render

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