Predicting protein function and orientation on a gold nanoparticle surface using a residue-based affinity scale
The orientation of proteins on nanoparticle surfaces is important to the nanoparticle’s fate in vivo. Here, the authors use competitive binding between protein variants to develop a residue-based affinity scale to develop a model for the binding and orientation of proteins on gold nanoparticles
Main Authors: | Joanna Xiuzhu Xu, Md. Siddik Alom, Rahul Yadav, Nicholas C. Fitzkee |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-34749-w |
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