Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2

Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2

Fibrinogen-like protein 2 (Fgl2) is critical for immune regulation in the inflammatory state. Elevated Fgl2 levels are observed in patients with inflammatory bowel disease (IBD), but little is known about its functional significance. In this study, we sought to investigate the role of Fgl2 in the de...

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Bibliographic Details
Main Authors: Ying Zhu, Jie Zhou, Yi Feng, Liying Chen, Longhui Zhang, Fei Yang, Haoran Zha, Xinxin Wang, Xiao Han, Chi Shu, Yisong Y. Wan, Qi-Jing Li, Bo Guo, Bo Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
fibrinogen-like protein 2
colitis
colitis-associated colorectal cancer
immune regulation
intestinal inflammation
macrophage polarization
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00087/full

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