Retroviral Vectors for Analysis of Viral Mutagenesis and Recombination

Retroviral Vectors for Analysis of Viral Mutagenesis and Recombination

Retrovirus population diversity within infected hosts is commonly high due in part to elevated rates of replication, mutation, and recombination. This high genetic diversity often complicates the development of effective diagnostics, vaccines, and antiviral drugs. This review highlights the diverse...

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Bibliographic Details
Main Authors: Jonathan M.O. Rawson, Louis M. Mansky
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Viruses
Subjects:
retrovirus
lentivirus
reverse transcription
evolution
mutation
recombination
retroviral vector
Online Access:http://www.mdpi.com/1999-4915/6/9/3612

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