New Polyene Macrolide Compounds from Mangrove-Derived Strain <i>Streptomyces hiroshimensis</i> GXIMD 06359: Isolation, Antifungal Activity, and Mechanism against <i>Talaromyces marneffei</i>

New Polyene Macrolide Compounds from Mangrove-Derived Strain <i>Streptomyces hiroshimensis</i> GXIMD 06359: Isolation, Antifungal Activity, and Mechanism against <i>Talaromyces marneffei</i>

Mangrove-derived actinomycetes represent a rich source of novel bioactive natural products in drug discovery. In this study, four new polyene macrolide antibiotics antifungalmycin B-E (<b>1</b>–<b>4</b>), along with seven known analogs (<b>5</b>–<b>11</b&...

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Bibliographic Details
Main Authors: Zhou Wang, Jianglin Yin, Meng Bai, Jie Yang, Cuiping Jiang, Xiangxi Yi, Yonghong Liu, Chenghai Gao
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Marine Drugs
Subjects:
actinomycetes
polyene macrolide
<i>Streptomyces hiroshimensis</i>
antifungal activity
antifungal mechanism
<i>Talaromyces marneffei</i>
Online Access:https://www.mdpi.com/1660-3397/22/1/38

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