Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of <i>Lamiaceae</i> species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attenti...
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| Format: | Article |
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MDPI AG
2023-10-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/19/4297 |
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| author | Md. Khabeer Azhar Saleha Anwar Gulam Mustafa Hasan Anas Shamsi Asimul Islam Suhel Parvez Md. Imtaiyaz Hassan |
| author_facet | Md. Khabeer Azhar Saleha Anwar Gulam Mustafa Hasan Anas Shamsi Asimul Islam Suhel Parvez Md. Imtaiyaz Hassan |
| author_sort | Md. Khabeer Azhar |
| collection | DOAJ |
| description | Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of <i>Lamiaceae</i> species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders. |
| first_indexed | 2024-03-10T21:38:07Z |
| format | Article |
| id | doaj.art-ce7feaf4ca924746bd1fd199f7087b1e |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T21:38:07Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-ce7feaf4ca924746bd1fd199f7087b1e2023-11-19T14:52:56ZengMDPI AGNutrients2072-66432023-10-011519429710.3390/nu15194297Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative DiseasesMd. Khabeer Azhar0Saleha Anwar1Gulam Mustafa Hasan2Anas Shamsi3Asimul Islam4Suhel Parvez5Md. Imtaiyaz Hassan6Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, IndiaDepartment of Toxicology, School of Chemical & Life Sciences, Jamia Hamdard, New Delhi 110062, IndiaDepartment of Basic Medical Science, College of Medicine, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj 11942, Saudi ArabiaCentre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman 364, United Arab EmiratesCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, IndiaDepartment of Toxicology, School of Chemical & Life Sciences, Jamia Hamdard, New Delhi 110062, IndiaCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, IndiaPhytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of <i>Lamiaceae</i> species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders.https://www.mdpi.com/2072-6643/15/19/4297anticancer therapeuticsphytochemicalsneurodegenerative diseasesrosmarinic acidantioxidantanti-inflammatory |
| spellingShingle | Md. Khabeer Azhar Saleha Anwar Gulam Mustafa Hasan Anas Shamsi Asimul Islam Suhel Parvez Md. Imtaiyaz Hassan Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases Nutrients anticancer therapeutics phytochemicals neurodegenerative diseases rosmarinic acid antioxidant anti-inflammatory |
| title | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
| title_full | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
| title_fullStr | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
| title_full_unstemmed | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
| title_short | Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases |
| title_sort | comprehensive insights into biological roles of rosmarinic acid implications in diabetes cancer and neurodegenerative diseases |
| topic | anticancer therapeutics phytochemicals neurodegenerative diseases rosmarinic acid antioxidant anti-inflammatory |
| url | https://www.mdpi.com/2072-6643/15/19/4297 |
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