Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome

Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome

Our objectives are to demonstrate whether the kynurenine pathway is activated in diarrhea-type irritable bowel syndrome (IBS-D) patients, and whether the neurotoxic metabolite quinolinic acid (QUIN) is out of balance with the neuroprotective metabolite kynurenic acid (KYNA), and further explore whet...

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Bibliographic Details
Main Authors: Pingping Li, Jimin Zheng, Yun Bai, Dingxin Wang, Zijin Cui, Yueqin Li, Jian Zhang, Yuzhen Wang
Format: Article
Language:English
Published: PAGEPress Publications 2020-06-01
Series:European Journal of Histochemistry
Subjects:
irritable bowel syndrome
kynurenine pathway
kynurenic acid
quinolinic acid
N-methyl D-aspartate receptor
Online Access:https://www.ejh.it/index.php/ejh/article/view/3132

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