An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease
Pneumatosis intestinalis (PI) is a rare disease, which presents a wide range of severity. Numerous etiologies, including trauma, inflammation, infections, autoimmunity, drugs, and mechanical procedures, gave rise to this complication. Abdominal computerized tomography is the preferred diagnostic too...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2021-12-01
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| Series: | Türk Yoğun Bakim Derneği Dergisi |
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http://www.turkishjic.org/archives/archive-detail/article-preview/an-exceptional-etiology-of-a-rare-disease-pneumato/49036
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| _version_ | 1797922561285160960 |
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| author | Taner Çalışkan Hüseyin Özkök Murat Küçük Beril Turan Erdoğan Vedat Uygun Yusuf Savran Bilgin Cömert |
| author_facet | Taner Çalışkan Hüseyin Özkök Murat Küçük Beril Turan Erdoğan Vedat Uygun Yusuf Savran Bilgin Cömert |
| author_sort | Taner Çalışkan |
| collection | DOAJ |
| description | Pneumatosis intestinalis (PI) is a rare disease, which presents a wide range of severity. Numerous etiologies, including trauma, inflammation, infections, autoimmunity, drugs, and mechanical procedures, gave rise to this complication. Abdominal computerized tomography is the preferred diagnostic tool with high sensitivity. The diagnosis depends on free air detection in the intramural portion of the gastrointestinal system and main and intrahepatic branches of the portal venous structures. However, the exact mechanism is unknown. The clinical scenario may vary from benign to life-threatening. One of the etiological factors that cause PI is the chronic graft-versus-host disease (cGVHD), which must be considered in patients with solid organ or hematological malignancies. Especially, patients who received long-term immunosuppressive therapies and were diagnosed with cGVHD are prone to developing a PI. Many patients experience unnecessary operational risks if underdiagnosed. A multidisciplinary approach by the primary physician, general surgeon, and radiology specialist is necessary for the proper treatment of these patients. This case report aimed to discuss the clinical presentation of PI in the course of cGVHD in the intensive care unit. |
| first_indexed | 2024-04-10T14:33:15Z |
| format | Article |
| id | doaj.art-ce8742c3bd0d4ec3bd45d2e214c895a0 |
| institution | Directory Open Access Journal |
| issn | 2146-6416 2147-267X |
| language | English |
| last_indexed | 2024-04-10T14:33:15Z |
| publishDate | 2021-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Yoğun Bakim Derneği Dergisi |
| spelling | doaj.art-ce8742c3bd0d4ec3bd45d2e214c895a02023-02-15T16:08:42ZengGalenos YayineviTürk Yoğun Bakim Derneği Dergisi2146-64162147-267X2021-12-0119420020410.4274/tybd.galenos.2021.5526513049054An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host DiseaseTaner Çalışkan0Hüseyin Özkök1Murat Küçük2Beril Turan Erdoğan3Vedat Uygun4Yusuf Savran5Bilgin Cömert6 Dokuz Eylül University Faculty of Medicine, Medical Intensive Care Unit, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Medical Intensive Care Unit, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Medical Intensive Care Unit, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Medical Intensive Care Unit, İzmir, Turkey Medical Park Antalya Hospital, Pediatric Bone Marrow Transplantation Unit, Antalya, Turkey Dokuz Eylül University Faculty of Medicine, Medical Intensive Care Unit, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Medical Intensive Care Unit, İzmir, Turkey Pneumatosis intestinalis (PI) is a rare disease, which presents a wide range of severity. Numerous etiologies, including trauma, inflammation, infections, autoimmunity, drugs, and mechanical procedures, gave rise to this complication. Abdominal computerized tomography is the preferred diagnostic tool with high sensitivity. The diagnosis depends on free air detection in the intramural portion of the gastrointestinal system and main and intrahepatic branches of the portal venous structures. However, the exact mechanism is unknown. The clinical scenario may vary from benign to life-threatening. One of the etiological factors that cause PI is the chronic graft-versus-host disease (cGVHD), which must be considered in patients with solid organ or hematological malignancies. Especially, patients who received long-term immunosuppressive therapies and were diagnosed with cGVHD are prone to developing a PI. Many patients experience unnecessary operational risks if underdiagnosed. A multidisciplinary approach by the primary physician, general surgeon, and radiology specialist is necessary for the proper treatment of these patients. This case report aimed to discuss the clinical presentation of PI in the course of cGVHD in the intensive care unit. http://www.turkishjic.org/archives/archive-detail/article-preview/an-exceptional-etiology-of-a-rare-disease-pneumato/49036 chronic graft versus host diseasepneumatosis intestinalisintensive care |
| spellingShingle | Taner Çalışkan Hüseyin Özkök Murat Küçük Beril Turan Erdoğan Vedat Uygun Yusuf Savran Bilgin Cömert An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease Türk Yoğun Bakim Derneği Dergisi chronic graft versus host disease pneumatosis intestinalis intensive care |
| title | An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease |
| title_full | An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease |
| title_fullStr | An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease |
| title_full_unstemmed | An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease |
| title_short | An Exceptional Etiology of a Rare Disease: Pneumatosis Intestinalis in the Intensive Care Unit due to Chronic Graft-Versus-Host Disease |
| title_sort | exceptional etiology of a rare disease pneumatosis intestinalis in the intensive care unit due to chronic graft versus host disease |
| topic | chronic graft versus host disease pneumatosis intestinalis intensive care |
| url |
http://www.turkishjic.org/archives/archive-detail/article-preview/an-exceptional-etiology-of-a-rare-disease-pneumato/49036
|
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