Impact of a phage cocktail targeting Escherichia coli and Enterococcus faecalis as members of a gut bacterial consortium in vitro and in vivo

Impact of a phage cocktail targeting Escherichia coli and Enterococcus faecalis as members of a gut bacterial consortium in vitro and in vivo

Escherichia coli and Enterococcus faecalis have been implicated as important players in human gut health that have been associated with the onset of inflammatory bowel disease (IBD). Bacteriophage (phage) therapy has been used for decades to target pathogens as an alternative to antibiotics, but the...

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Bibliographic Details
Main Authors: Colin Buttimer, Tom Sutton, Joan Colom, Ellen Murray, Pedro H. Bettio, Linda Smith, Andrei S. Bolocan, Andrey Shkoporov, Akihiko Oka, Bo Liu, Jeremy W. Herzog, R. Balfour Sartor, Lorraine A. Draper, R. Paul Ross, Colin Hill
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Microbiology
Subjects:
bacteriophage
phage cocktail therapy
bacteria consortium
Escherichia coli
Enterococcus faecalis
gut
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.936083/full

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