Efficacy and safety of amphotericin B deoxycholate versus N-methylglucamine antimoniate in pediatric visceral leishmaniasis: an open-label, randomized, and controlled pilot trial in Brazil

Efficacy and safety of amphotericin B deoxycholate versus N-methylglucamine antimoniate in pediatric visceral leishmaniasis: an open-label, randomized, and controlled pilot trial in Brazil

ABSTRACT INTRODUCTION Despite their high toxicity, antimonials and amphotericin B deoxycholate are commonly used for treating visceral leishmaniasis (VL). Few studies showing conflictive data about their efficacy and adverse events in pediatric population are available. This study aimed to evaluat...

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Bibliographic Details
Main Authors: Myrlena Mescouto Borges, Maria Cristina da Silva Pranchevicius, Elza Ferreira Noronha, Gustavo Adolfo Sierra Romero, César Omar Carranza-Tamayo
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT)
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Visceral leishmaniasis
Children
Clinical trial
Brazil
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000100067&lng=en&tlng=en

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