Breaking the Cycle of Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation
Heart failure with preserved ejection fraction (HFpEF) and AF are two common cardiovascular conditions that are inextricably linked to each other’s development and progression, often in multimorbid patients. Current management is often directed to specific components of each disease without consider...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Radcliffe Medical Media
2022-11-01
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| Series: | Cardiac Failure Review |
| Online Access: | https://www.cfrjournal.com/articleindex/cfr.2022.03 |
| _version_ | 1797200010999234560 |
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| author | Otilia Țica Waseem Khamboo Dipak Kotecha |
| author_facet | Otilia Țica Waseem Khamboo Dipak Kotecha |
| author_sort | Otilia Țica |
| collection | DOAJ |
| description | Heart failure with preserved ejection fraction (HFpEF) and AF are two common cardiovascular conditions that are inextricably linked to each other’s development and progression, often in multimorbid patients. Current management is often directed to specific components of each disease without considering their joint impact on diagnosis, treatment and prognosis. The result for patients is suboptimal on all three levels, restricting clinicians from preventing major adverse events, including death, which occurs in 20% of patients at 2 years and in 45% at 4 years. New trial evidence and reanalysis of prior trials are providing a glimmer of hope that adverse outcomes can be reduced in those with concurrent HFpEF and AF. This will require a restructuring of care to integrate heart failure and AF teams, alongside those that manage comorbidities. Parallel commencement and non-sequential uptitration of therapeutics across different domains will be vital to ensure that all patients benefit at a personal level, based on their own needs and priorities. |
| first_indexed | 2024-03-07T17:40:19Z |
| format | Article |
| id | doaj.art-ce8ef6ae85264d21b405edf2441faff0 |
| institution | Directory Open Access Journal |
| issn | 2057-7540 2057-7559 |
| language | English |
| last_indexed | 2024-04-24T07:24:51Z |
| publishDate | 2022-11-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Cardiac Failure Review |
| spelling | doaj.art-ce8ef6ae85264d21b405edf2441faff02024-04-20T16:03:06ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592022-11-01810.15420/cfr.2022.03Breaking the Cycle of Heart Failure With Preserved Ejection Fraction and Atrial FibrillationOtilia Țica0Waseem Khamboo1Dipak Kotecha2Institute of Cardiovascular Sciences, University of Birmingham, Medical School, Birmingham, UK; Cardiology Department, Emergency County Clinical Hospital of Oradea, Oradea, RomaniaInstitute of Cardiovascular Sciences, University of Birmingham, Medical School, Birmingham, UKInstitute of Cardiovascular Sciences, University of Birmingham, Medical School, Birmingham, UK; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UKHeart failure with preserved ejection fraction (HFpEF) and AF are two common cardiovascular conditions that are inextricably linked to each other’s development and progression, often in multimorbid patients. Current management is often directed to specific components of each disease without considering their joint impact on diagnosis, treatment and prognosis. The result for patients is suboptimal on all three levels, restricting clinicians from preventing major adverse events, including death, which occurs in 20% of patients at 2 years and in 45% at 4 years. New trial evidence and reanalysis of prior trials are providing a glimmer of hope that adverse outcomes can be reduced in those with concurrent HFpEF and AF. This will require a restructuring of care to integrate heart failure and AF teams, alongside those that manage comorbidities. Parallel commencement and non-sequential uptitration of therapeutics across different domains will be vital to ensure that all patients benefit at a personal level, based on their own needs and priorities.https://www.cfrjournal.com/articleindex/cfr.2022.03 |
| spellingShingle | Otilia Țica Waseem Khamboo Dipak Kotecha Breaking the Cycle of Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation Cardiac Failure Review |
| title | Breaking the Cycle of Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation |
| title_full | Breaking the Cycle of Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation |
| title_fullStr | Breaking the Cycle of Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation |
| title_full_unstemmed | Breaking the Cycle of Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation |
| title_short | Breaking the Cycle of Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation |
| title_sort | breaking the cycle of heart failure with preserved ejection fraction and atrial fibrillation |
| url | https://www.cfrjournal.com/articleindex/cfr.2022.03 |
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