Xerostomia in Patients with Chronic Renal Failure Undergoing Hemodialysis
BACKGROUND AND OBJECTIVE: Chronic renal failure may affect the oral cavity because of the variety of metabolic and pathophysiologic changes. The aim of this study was to compare the xerostomia in unstimulated and pilocarpine-stimulated whole saliva of hemodialysis patients with the control group....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Babol University of Medical Sciences
2014-10-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| Subjects: | |
| Online Access: | http://jbums.org/browse.php?a_code=A-10-583-1&slc_lang=en&sid=1 |
| Summary: | BACKGROUND AND
OBJECTIVE: Chronic
renal failure may affect the oral cavity because of the variety of metabolic
and pathophysiologic changes. The aim of this study was to compare the
xerostomia in unstimulated and pilocarpine-stimulated whole
saliva of hemodialysis patients with the control group.
METHODS: This
cross-sectional study was conducted on 30 hemodialysis patients aged range of
35 to 65 and 30 healthy volunteers as control group. Patients’ individual data
such as age, sex and duration of hemodialysis and their complaining of xerostomia,
taste change and malodor were recorded. The xerostomia status of patients was
evaluated by filling out the standard questionnaires. To determine the salivary
changes unstimulated and pilocarpine-stimulated whole saliva was collected from
both the patient and the control groups..
FINDINGS: Complaining of xerostomia was the most common oral
manifestations among the patients. Dry mouth , taste change and malodor were recorded
in 19 (63.3%), 14 (46.7%) and 14 (46.7%) of the patients, respectively. The
unstimulated whole saliva was significantly lower in hemodialysis patients compared
toin the control group (p<0.05). In
addition, stimulated whole saliva was significantly lower in patients underwent
hemodialysis (p<0.05).
CONCLUSION: The results showed that the decrease
of unstimulated and pilocarpine-stimulated whole saliva in hemodialysis
patients compared to the control group may cause xerostomia in these patients. |
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| ISSN: | 1561-4107 2251-7170 |