Comparison of Different Topographic Reference Surfaces in Keratoconus Cases

OBJECTİVE: To compare the sensitivity and specificity of elevation maps obtained from different topographical reference surfaces used in the diagnosis of keratoconus. MATERİALS AND METHODS: In this study 40 eyes of 23 patients with keratoconus and 40 eyes of 25 refractive surgery candidates as a...

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Main Authors: Ahmet Elbeyli, Sucattin Kocamis, Hasan Çakmak, Emine Doğan
Format: Article
Language:English
Published: Sakarya University 2021-03-01
Series:Sakarya Tıp Dergisi
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/1134063
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author Ahmet Elbeyli
Sucattin Kocamis
Hasan Çakmak
Emine Doğan
author_facet Ahmet Elbeyli
Sucattin Kocamis
Hasan Çakmak
Emine Doğan
author_sort Ahmet Elbeyli
collection DOAJ
description OBJECTİVE: To compare the sensitivity and specificity of elevation maps obtained from different topographical reference surfaces used in the diagnosis of keratoconus. MATERİALS AND METHODS: In this study 40 eyes of 23 patients with keratoconus and 40 eyes of 25 refractive surgery candidates as a control group was measured with a Scheimpflug camera (Sirius CSO-Italy). Using the receiver operator characteristic curves (ROC), a comparison was made of the ability to differentiate keratoconus from a normal cornea with anterior elevation(AE) and posterior elevation(PE) measurements obtained from the spherical, aspherical, asphero-toric reference surfaces. RESULTS: The ROC curve analysis showed that posterior elevation measured from the aspherical and asphero-toric surfaces had a significantly higher area under the ROC curves (0.987, 0.973 respectively) thanthevalueobtainedfromthesphericalreferencesurfaces. According to the data obtained from the ROC curve analysis, the posterior elevation maps obtained from the aspherical and asphero-toric reference surfaces had the highest sensitivity (97.5% for both) and the posterior elevation map obtained from the aspherical reference surface had the highest specificity (90%). CONCLUSION: The highest sensitivity and specificity values were obtained from the aspherical and asphero-toric reference surfaces rather than from the spherical reference surface. When compared to the anterior elevation values, the posterior elevation values were found to be more sensitive and specific. Therefore, aspherical and asphero-toric reference surfaces and a posterior elevation map would seem to be more accurate in the differentiation of keratoconus and normal cornea.
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spelling doaj.art-ce8fe70223e24794aafc7f041570e4d42024-01-21T07:40:10ZengSakarya UniversitySakarya Tıp Dergisi2146-409X2021-03-01111778410.31832/smj.74756028Comparison of Different Topographic Reference Surfaces in Keratoconus CasesAhmet Elbeyli0Sucattin Kocamis1Hasan Çakmak2Emine Doğan3MUSTAFA KEMAL ÜNİVERSİTESİSAKARYA YENİKENT DEVLET HASTANESİHITIT UNIVERSITYSAKARYA SAĞLIK BAKANLIĞI SAKARYA ÜNİVERSİTESİ EĞİTİM VE ARAŞTIRMA HASTANESİOBJECTİVE: To compare the sensitivity and specificity of elevation maps obtained from different topographical reference surfaces used in the diagnosis of keratoconus. MATERİALS AND METHODS: In this study 40 eyes of 23 patients with keratoconus and 40 eyes of 25 refractive surgery candidates as a control group was measured with a Scheimpflug camera (Sirius CSO-Italy). Using the receiver operator characteristic curves (ROC), a comparison was made of the ability to differentiate keratoconus from a normal cornea with anterior elevation(AE) and posterior elevation(PE) measurements obtained from the spherical, aspherical, asphero-toric reference surfaces. RESULTS: The ROC curve analysis showed that posterior elevation measured from the aspherical and asphero-toric surfaces had a significantly higher area under the ROC curves (0.987, 0.973 respectively) thanthevalueobtainedfromthesphericalreferencesurfaces. According to the data obtained from the ROC curve analysis, the posterior elevation maps obtained from the aspherical and asphero-toric reference surfaces had the highest sensitivity (97.5% for both) and the posterior elevation map obtained from the aspherical reference surface had the highest specificity (90%). CONCLUSION: The highest sensitivity and specificity values were obtained from the aspherical and asphero-toric reference surfaces rather than from the spherical reference surface. When compared to the anterior elevation values, the posterior elevation values were found to be more sensitive and specific. Therefore, aspherical and asphero-toric reference surfaces and a posterior elevation map would seem to be more accurate in the differentiation of keratoconus and normal cornea.https://dergipark.org.tr/tr/download/article-file/1134063keratokonuskorneakorneal topografireferans yüzey seçimischeimpflug kamerascheimpflug cameracorneacorneal topographykeratoconusreference body selection
spellingShingle Ahmet Elbeyli
Sucattin Kocamis
Hasan Çakmak
Emine Doğan
Comparison of Different Topographic Reference Surfaces in Keratoconus Cases
Sakarya Tıp Dergisi
keratokonus
kornea
korneal topografi
referans yüzey seçimi
scheimpflug kamera
scheimpflug camera
cornea
corneal topography
keratoconus
reference body selection
title Comparison of Different Topographic Reference Surfaces in Keratoconus Cases
title_full Comparison of Different Topographic Reference Surfaces in Keratoconus Cases
title_fullStr Comparison of Different Topographic Reference Surfaces in Keratoconus Cases
title_full_unstemmed Comparison of Different Topographic Reference Surfaces in Keratoconus Cases
title_short Comparison of Different Topographic Reference Surfaces in Keratoconus Cases
title_sort comparison of different topographic reference surfaces in keratoconus cases
topic keratokonus
kornea
korneal topografi
referans yüzey seçimi
scheimpflug kamera
scheimpflug camera
cornea
corneal topography
keratoconus
reference body selection
url https://dergipark.org.tr/tr/download/article-file/1134063
work_keys_str_mv AT ahmetelbeyli comparisonofdifferenttopographicreferencesurfacesinkeratoconuscases
AT sucattinkocamis comparisonofdifferenttopographicreferencesurfacesinkeratoconuscases
AT hasancakmak comparisonofdifferenttopographicreferencesurfacesinkeratoconuscases
AT eminedogan comparisonofdifferenttopographicreferencesurfacesinkeratoconuscases