Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia
Narcolepsy and idiopathic hypersomnia are central disorders of hypersomnolence accompanied by excessive daytime sleepiness, which are not caused by nocturnal sleep disturbance, sleep deficiency, or circadian rhythm sleep disorders. Several studies have questioned the repeatability of the Multiple Sl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Sleep Medicine
2023-03-01
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| Series: | Sleep Medicine Research |
| Subjects: | |
| Online Access: | http://sleepmedres.org/upload/pdf/smr-2023-01669.pdf |
| _version_ | 1827964787735134208 |
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| author | Seung-Chul Hong Ji Hyun Song Tae-Won Kim Young-Chan Kim |
| author_facet | Seung-Chul Hong Ji Hyun Song Tae-Won Kim Young-Chan Kim |
| author_sort | Seung-Chul Hong |
| collection | DOAJ |
| description | Narcolepsy and idiopathic hypersomnia are central disorders of hypersomnolence accompanied by excessive daytime sleepiness, which are not caused by nocturnal sleep disturbance, sleep deficiency, or circadian rhythm sleep disorders. Several studies have questioned the repeatability of the Multiple Sleep Latency Test (MSLT) in type 2 narcolepsy (NT2) patients. After two or more repeated MSLTs, the diagnosis of type 1 narcolepsy (NT1) is maintained in more than 90% of cases, while only half of the NT2 patients retain their original diagnosis. The diagnosis of NT2 may shift to idiopathic hypersomnia based on the MSLT results, making the differential diagnosis of NT2 and idiopathic hypersomnia particularly challenging. Therefore, this study suggests the need for new tests in addition to the MSLT for diagnostic consistency in NT2 and idiopathic hypersomnia. |
| first_indexed | 2024-04-09T17:22:00Z |
| format | Article |
| id | doaj.art-ce954b7de6bc44b9990fba6d39625d93 |
| institution | Directory Open Access Journal |
| issn | 2093-9175 2233-8853 |
| language | English |
| last_indexed | 2024-04-09T17:22:00Z |
| publishDate | 2023-03-01 |
| publisher | Korean Society of Sleep Medicine |
| record_format | Article |
| series | Sleep Medicine Research |
| spelling | doaj.art-ce954b7de6bc44b9990fba6d39625d932023-04-19T01:51:26ZengKorean Society of Sleep MedicineSleep Medicine Research2093-91752233-88532023-03-011416910.17241/smr.2023.01669228Challenges in Diagnosing Narcolepsy and Idiopathic HypersomniaSeung-Chul Hong0Ji Hyun Song1Tae-Won Kim2Young-Chan Kim3 Department of Psychiatry, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea Sleep Disorders Clinic, Department of Psychiatry, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea Department of Psychiatry, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea Department of Psychiatry, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, KoreaNarcolepsy and idiopathic hypersomnia are central disorders of hypersomnolence accompanied by excessive daytime sleepiness, which are not caused by nocturnal sleep disturbance, sleep deficiency, or circadian rhythm sleep disorders. Several studies have questioned the repeatability of the Multiple Sleep Latency Test (MSLT) in type 2 narcolepsy (NT2) patients. After two or more repeated MSLTs, the diagnosis of type 1 narcolepsy (NT1) is maintained in more than 90% of cases, while only half of the NT2 patients retain their original diagnosis. The diagnosis of NT2 may shift to idiopathic hypersomnia based on the MSLT results, making the differential diagnosis of NT2 and idiopathic hypersomnia particularly challenging. Therefore, this study suggests the need for new tests in addition to the MSLT for diagnostic consistency in NT2 and idiopathic hypersomnia.http://sleepmedres.org/upload/pdf/smr-2023-01669.pdfnarcolepsyhypersomniapolysomnographymslt |
| spellingShingle | Seung-Chul Hong Ji Hyun Song Tae-Won Kim Young-Chan Kim Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia Sleep Medicine Research narcolepsy hypersomnia polysomnography mslt |
| title | Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia |
| title_full | Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia |
| title_fullStr | Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia |
| title_full_unstemmed | Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia |
| title_short | Challenges in Diagnosing Narcolepsy and Idiopathic Hypersomnia |
| title_sort | challenges in diagnosing narcolepsy and idiopathic hypersomnia |
| topic | narcolepsy hypersomnia polysomnography mslt |
| url | http://sleepmedres.org/upload/pdf/smr-2023-01669.pdf |
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