Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis

Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis

Abstract Background Type I polyketide synthases (PKSs) are multifunctional enzymes responsible for the biosynthesis of a group of diverse natural compounds with biotechnological and pharmaceutical interest called polyketides. The diversity of polyketides is impressive despite the limited set of cata...

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Bibliographic Details
Main Authors: Cécile Bon, Stéphanie Cabantous, Sylviane Julien, Valérie Guillet, Christian Chalut, Julie Rima, Yoann Brison, Wladimir Malaga, Angelique Sanchez-Dafun, Sabine Gavalda, Annaïk Quémard, Julien Marcoux, Geoffrey S. Waldo, Christophe Guilhot, Lionel Mourey
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Biology
Subjects:
Mycolic acids
Polyketide synthases
Small-angle X-ray scattering
3D structure
Online Access:https://doi.org/10.1186/s12915-022-01337-9

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