Abstract OR-5: Prediction of Relaxed Conformations for Tubulin Dimers: from Cryo- Electron Microscopy to Molecular Dynamics

Abstract OR-5: Prediction of Relaxed Conformations for Tubulin Dimers: from Cryo- Electron Microscopy to Molecular Dynamics

Background: Tubulin microtubules are essential cytoskeletal filaments, with diverse and critical functions at all stages of the cell cycle. Tubulin dimers, which serve as main building blocks for microtubules, can self-assemble and disassemble, depending on the phosphorylation state of associated nu...

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Bibliographic Details
Main Authors: Vladimir A. Fedorov, Philipp S. Orekhov, Ekaterina G. Kholina, Ilya B. Kovalenko, Nikita B. Gudimchuk
Format: Article
Language:English
Published: International Medical Research and Development Corporation 2019-06-01
Series:International Journal of Biomedicine
Subjects:
microtubules
tubulin
cryo-electron microscopy
conformation
Online Access:http://ijbm.org/articles/ijbm_2019_9_s1_or5.pdf

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