Histone H3 variants at the root of metastasis

Chromatin remodeling is at the root of any cell fate decision, laying the foundation for the necessary reprogramming to occur. Our work shows histone H3 variants as a new addition to the ever-growing body of epigenetic regulators, one that is essential for cell fate transitions in carcinoma cells to...

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Main Authors: Didem Ilter, John Blenis, Ana P. Gomes
Format: Article
Language:English
Published: Taylor & Francis Group 2020-03-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2019.1684128
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author Didem Ilter
John Blenis
Ana P. Gomes
author_facet Didem Ilter
John Blenis
Ana P. Gomes
author_sort Didem Ilter
collection DOAJ
description Chromatin remodeling is at the root of any cell fate decision, laying the foundation for the necessary reprogramming to occur. Our work shows histone H3 variants as a new addition to the ever-growing body of epigenetic regulators, one that is essential for cell fate transitions in carcinoma cells to promote tumor progression and metastasis.
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spelling doaj.art-cea5c04e45aa43618f571ddfb73567f52023-09-22T09:11:01ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562020-03-017210.1080/23723556.2019.16841281684128Histone H3 variants at the root of metastasisDidem Ilter0John Blenis1Ana P. Gomes2Weill Cornell MedicineWeill Cornell MedicineWeill Cornell MedicineChromatin remodeling is at the root of any cell fate decision, laying the foundation for the necessary reprogramming to occur. Our work shows histone H3 variants as a new addition to the ever-growing body of epigenetic regulators, one that is essential for cell fate transitions in carcinoma cells to promote tumor progression and metastasis.http://dx.doi.org/10.1080/23723556.2019.1684128tumor progressionmetastasisepigeneticshistone h3.3histone chaperones
spellingShingle Didem Ilter
John Blenis
Ana P. Gomes
Histone H3 variants at the root of metastasis
Molecular & Cellular Oncology
tumor progression
metastasis
epigenetics
histone h3.3
histone chaperones
title Histone H3 variants at the root of metastasis
title_full Histone H3 variants at the root of metastasis
title_fullStr Histone H3 variants at the root of metastasis
title_full_unstemmed Histone H3 variants at the root of metastasis
title_short Histone H3 variants at the root of metastasis
title_sort histone h3 variants at the root of metastasis
topic tumor progression
metastasis
epigenetics
histone h3.3
histone chaperones
url http://dx.doi.org/10.1080/23723556.2019.1684128
work_keys_str_mv AT didemilter histoneh3variantsattherootofmetastasis
AT johnblenis histoneh3variantsattherootofmetastasis
AT anapgomes histoneh3variantsattherootofmetastasis