Histone H3 variants at the root of metastasis
Chromatin remodeling is at the root of any cell fate decision, laying the foundation for the necessary reprogramming to occur. Our work shows histone H3 variants as a new addition to the ever-growing body of epigenetic regulators, one that is essential for cell fate transitions in carcinoma cells to...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2020-03-01
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Series: | Molecular & Cellular Oncology |
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Online Access: | http://dx.doi.org/10.1080/23723556.2019.1684128 |
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author | Didem Ilter John Blenis Ana P. Gomes |
author_facet | Didem Ilter John Blenis Ana P. Gomes |
author_sort | Didem Ilter |
collection | DOAJ |
description | Chromatin remodeling is at the root of any cell fate decision, laying the foundation for the necessary reprogramming to occur. Our work shows histone H3 variants as a new addition to the ever-growing body of epigenetic regulators, one that is essential for cell fate transitions in carcinoma cells to promote tumor progression and metastasis. |
first_indexed | 2024-03-11T22:41:12Z |
format | Article |
id | doaj.art-cea5c04e45aa43618f571ddfb73567f5 |
institution | Directory Open Access Journal |
issn | 2372-3556 |
language | English |
last_indexed | 2024-03-11T22:41:12Z |
publishDate | 2020-03-01 |
publisher | Taylor & Francis Group |
record_format | Article |
series | Molecular & Cellular Oncology |
spelling | doaj.art-cea5c04e45aa43618f571ddfb73567f52023-09-22T09:11:01ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562020-03-017210.1080/23723556.2019.16841281684128Histone H3 variants at the root of metastasisDidem Ilter0John Blenis1Ana P. Gomes2Weill Cornell MedicineWeill Cornell MedicineWeill Cornell MedicineChromatin remodeling is at the root of any cell fate decision, laying the foundation for the necessary reprogramming to occur. Our work shows histone H3 variants as a new addition to the ever-growing body of epigenetic regulators, one that is essential for cell fate transitions in carcinoma cells to promote tumor progression and metastasis.http://dx.doi.org/10.1080/23723556.2019.1684128tumor progressionmetastasisepigeneticshistone h3.3histone chaperones |
spellingShingle | Didem Ilter John Blenis Ana P. Gomes Histone H3 variants at the root of metastasis Molecular & Cellular Oncology tumor progression metastasis epigenetics histone h3.3 histone chaperones |
title | Histone H3 variants at the root of metastasis |
title_full | Histone H3 variants at the root of metastasis |
title_fullStr | Histone H3 variants at the root of metastasis |
title_full_unstemmed | Histone H3 variants at the root of metastasis |
title_short | Histone H3 variants at the root of metastasis |
title_sort | histone h3 variants at the root of metastasis |
topic | tumor progression metastasis epigenetics histone h3.3 histone chaperones |
url | http://dx.doi.org/10.1080/23723556.2019.1684128 |
work_keys_str_mv | AT didemilter histoneh3variantsattherootofmetastasis AT johnblenis histoneh3variantsattherootofmetastasis AT anapgomes histoneh3variantsattherootofmetastasis |