Resistance Rates to Selected Antibiotics in Gram Negative Bacteria Isolated from Intensive Care Units (ICU) in Turkish Hospitals
As a result of the extensive use of new generation cephalosporins, an increase in the frequency of gram negative bacteria in nosocomial infections is observed in recent years. Awareness of the rate of resistance to these agents is a requirement in order to install apropriate control measured. A stud...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bilimsel Tip Yayinevi
1996-09-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=1996-1-3-153-159.pdf |
| Summary: | As a result of the extensive use of new generation cephalosporins, an increase in the frequency of gram negative bacteria in nosocomial infections is observed in recent years. Awareness of the rate of resistance to these agents is a requirement in order to install apropriate control measured. A study was undertaken with the participation of nine hospitals in Turkey to determine the frequency of gram negative bacteria isolated in the ICU’s and compare the resistance rates to selected antibiotics. 981 bacteria were collected and antibiotic susceptibilities were determined by E-test. Pseudomonas spp. was the most prevalent organism (30%) followed by Klebsiella spp. (25%) and E. coli (18%). Imipenem, amikacin and ciprofloxacin were the most active agents in vitro with slight variations according to each center. The high rate of resistance to the new generation cephalosporins suggested the Class I and extended-broad-spectrum ß-lactamases. |
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| ISSN: | 1300-932X 1300-932X |