Opto-APC: Engineering of cells that display phytochrome B on their surface for optogenetic studies of cell-cell interactions

Opto-APC: Engineering of cells that display phytochrome B on their surface for optogenetic studies of cell-cell interactions

The kinetics of a ligand-receptor interaction determine the responses of the receptor-expressing cell. One approach to experimentally and reversibly change this kinetics on demand is optogenetics. We have previously developed a system in which the interaction of a modified receptor with an engineere...

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Bibliographic Details
Main Authors: Marissa Russ, Anna K. Ehret, Maximilian Hörner, Daniel Peschkov, Rebecca Bohnert, Vincent Idstein, Susana Minguet, Wilfried Weber, Björn F. Lillemeier, O. Sascha Yousefi, Wolfgang W. Schamel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
T cell receptor
ligand
receptor
optogenetics
interaction
phytochrome B
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1143274/full

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