A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma

<p>Abstract</p> <p>Metastatic leptomeningeal carcinomatosis is estimated to occur in 3% to 8% of solid carcinomas. The most common causes of leptomeningeal carcinomatosis are breast cancer, lung cancer and malignant melanoma. Leptomeningeal carcinomatosis associated with gastric ca...

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Main Authors: Park Kwang-Kuk, Yang Song-I, Seo Kyung-Won, Kim Young-Ok, Yoon Ki-Young
Format: Article
Language:English
Published: BMC 2012-05-01
Series:World Journal of Surgical Oncology
Subjects:
Online Access:http://www.wjso.com/content/10/1/74
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author Park Kwang-Kuk
Yang Song-I
Seo Kyung-Won
Kim Young-Ok
Yoon Ki-Young
author_facet Park Kwang-Kuk
Yang Song-I
Seo Kyung-Won
Kim Young-Ok
Yoon Ki-Young
author_sort Park Kwang-Kuk
collection DOAJ
description <p>Abstract</p> <p>Metastatic leptomeningeal carcinomatosis is estimated to occur in 3% to 8% of solid carcinomas. The most common causes of leptomeningeal carcinomatosis are breast cancer, lung cancer and malignant melanoma. Leptomeningeal carcinomatosis associated with gastric cancer, especially in its early stages, is exceedingly rare. Its presenting symptoms include headache, nauseaand seizures. In this report, we describe a case of leptomeningeal metastasis that presented with early-stage gastric cancer. A 67-year-old woman with a history of early-stage gastric cancer in remission was admitted to our hospital with 3 days of headache and nausea. Her gastric cancer had been treated 29 months prior to presentation by a radical subtotal gastrectomy with a Billroth I anastomosis. She had an uneventful recovery until she was diagnosed with metastases to the left axilla and neck 26 months after surgery. Her presenting symptoms of headache and nausea prompted cytologic examination of the cerebrospinal fluid and measurement of tumor markers, which revealed metastatic leptomeningeal carcinomatosis from her gastric cancer. This report aims to raise awareness of the possibility that even early-stage gastric cancer can lead to leptomeningeal carcinomatosis.</p>
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spelling doaj.art-ceadd03abef24f608f406745eda5bb162022-12-22T03:10:18ZengBMCWorld Journal of Surgical Oncology1477-78192012-05-011017410.1186/1477-7819-10-74A case of metastatic leptomeningeal carcinomatosis from early gastric carcinomaPark Kwang-KukYang Song-ISeo Kyung-WonKim Young-OkYoon Ki-Young<p>Abstract</p> <p>Metastatic leptomeningeal carcinomatosis is estimated to occur in 3% to 8% of solid carcinomas. The most common causes of leptomeningeal carcinomatosis are breast cancer, lung cancer and malignant melanoma. Leptomeningeal carcinomatosis associated with gastric cancer, especially in its early stages, is exceedingly rare. Its presenting symptoms include headache, nauseaand seizures. In this report, we describe a case of leptomeningeal metastasis that presented with early-stage gastric cancer. A 67-year-old woman with a history of early-stage gastric cancer in remission was admitted to our hospital with 3 days of headache and nausea. Her gastric cancer had been treated 29 months prior to presentation by a radical subtotal gastrectomy with a Billroth I anastomosis. She had an uneventful recovery until she was diagnosed with metastases to the left axilla and neck 26 months after surgery. Her presenting symptoms of headache and nausea prompted cytologic examination of the cerebrospinal fluid and measurement of tumor markers, which revealed metastatic leptomeningeal carcinomatosis from her gastric cancer. This report aims to raise awareness of the possibility that even early-stage gastric cancer can lead to leptomeningeal carcinomatosis.</p>http://www.wjso.com/content/10/1/74Early gastric cancerCarcinomatosisLeptomeningealSignet ring cell
spellingShingle Park Kwang-Kuk
Yang Song-I
Seo Kyung-Won
Kim Young-Ok
Yoon Ki-Young
A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma
World Journal of Surgical Oncology
Early gastric cancer
Carcinomatosis
Leptomeningeal
Signet ring cell
title A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma
title_full A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma
title_fullStr A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma
title_full_unstemmed A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma
title_short A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma
title_sort case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma
topic Early gastric cancer
Carcinomatosis
Leptomeningeal
Signet ring cell
url http://www.wjso.com/content/10/1/74
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