Variability in P2X receptor composition in human taste nerves: implications for treatment of chronic cough

Background Antagonists to the P2X purinergic receptors on airway sensory nerves relieve refractory or unexplained chronic cough (RCC/UCC) but can evoke unwanted dysgeusias because the gustatory nerves innervating taste buds express this same family of receptors. However, the subunit composition of t...

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Bibliographic Details
Main Authors: Brigit High, Marie E. Jetté, Mei Li, Vijay R. Ramakrishnan, Matthew Clary, Jeremy Prager, Julia Draf, Thomas Hummel, Thomas E. Finger
Format: Article
Language:English
Published: European Respiratory Society 2023-04-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/9/2/00007-2023.full