Extraction of Sungkai (Peronema cannescens Jack) leaves, Antioxidant Activity Test and Its Nanoemulsion Formulation
Sungkai (Peronema canescens J.) is an Indonesian native plant widely distributed on the islands of Kalimantan and Sumatra. Potential of these plants is related to the presence of secondary metabolites, which can be obtained through extraction. In its application, plant extract requires a delivery sy...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2024-01-01
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| Series: | E3S Web of Conferences |
| Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/33/e3sconf_isac-iccme2023_07008.pdf |
| _version_ | 1797248975681617920 |
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| author | Nurfauziyah Yulizar Yoki Meliana Yenny |
| author_facet | Nurfauziyah Yulizar Yoki Meliana Yenny |
| author_sort | Nurfauziyah |
| collection | DOAJ |
| description | Sungkai (Peronema canescens J.) is an Indonesian native plant widely distributed on the islands of Kalimantan and Sumatra. Potential of these plants is related to the presence of secondary metabolites, which can be obtained through extraction. In its application, plant extract requires a delivery system that can penetrate well into the skin and maximise the efficacy of the active ingredients, such as nanoemulsion, which has high kinetic stability due to the smaller droplet size. The research was conducted to compare the yields from the two extraction methods, the presence of active compounds in the plants related to their properties as antioxidants and then formulated into nanoemulsion. The results showed that Sungkai leaves extract contains active metabolites such as alkaloids, flavonoids, tannins and saponins. The extraction of sungkai leaves yields 15.91% and 14.71% for CE and UAE methods. The total phenolic and flavonoid values were 27.74 and 41.88 mg GAE/g extract; 17.60 and 36.02 mg QE/g extract; and IC50 values of 50.78 and 53.50, included in the strong antioxidant category. Stable nanoemulsion formulation was obtained by adding 1 gram of olive oil with a homogenisation speed of 15000 rpm, with particle size of 83.4 nm and a polydispersity index of 0.455. |
| first_indexed | 2024-04-24T20:23:08Z |
| format | Article |
| id | doaj.art-ceb3d3aa977842d7b6b7ab195d5e7960 |
| institution | Directory Open Access Journal |
| issn | 2267-1242 |
| language | English |
| last_indexed | 2024-04-24T20:23:08Z |
| publishDate | 2024-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj.art-ceb3d3aa977842d7b6b7ab195d5e79602024-03-22T07:56:07ZengEDP SciencesE3S Web of Conferences2267-12422024-01-015030700810.1051/e3sconf/202450307008e3sconf_isac-iccme2023_07008Extraction of Sungkai (Peronema cannescens Jack) leaves, Antioxidant Activity Test and Its Nanoemulsion FormulationNurfauziyah0Yulizar Yoki1Meliana Yenny2Chemistry Department, Faculty of Mathematic and Natural Sciences, University of IndonesiaChemistry Department, Faculty of Mathematic and Natural Sciences, University of IndonesiaResearch Centre for Chemistry, National Research and Innovation AgencySungkai (Peronema canescens J.) is an Indonesian native plant widely distributed on the islands of Kalimantan and Sumatra. Potential of these plants is related to the presence of secondary metabolites, which can be obtained through extraction. In its application, plant extract requires a delivery system that can penetrate well into the skin and maximise the efficacy of the active ingredients, such as nanoemulsion, which has high kinetic stability due to the smaller droplet size. The research was conducted to compare the yields from the two extraction methods, the presence of active compounds in the plants related to their properties as antioxidants and then formulated into nanoemulsion. The results showed that Sungkai leaves extract contains active metabolites such as alkaloids, flavonoids, tannins and saponins. The extraction of sungkai leaves yields 15.91% and 14.71% for CE and UAE methods. The total phenolic and flavonoid values were 27.74 and 41.88 mg GAE/g extract; 17.60 and 36.02 mg QE/g extract; and IC50 values of 50.78 and 53.50, included in the strong antioxidant category. Stable nanoemulsion formulation was obtained by adding 1 gram of olive oil with a homogenisation speed of 15000 rpm, with particle size of 83.4 nm and a polydispersity index of 0.455.https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/33/e3sconf_isac-iccme2023_07008.pdf |
| spellingShingle | Nurfauziyah Yulizar Yoki Meliana Yenny Extraction of Sungkai (Peronema cannescens Jack) leaves, Antioxidant Activity Test and Its Nanoemulsion Formulation E3S Web of Conferences |
| title | Extraction of Sungkai (Peronema cannescens Jack) leaves, Antioxidant Activity Test and Its Nanoemulsion Formulation |
| title_full | Extraction of Sungkai (Peronema cannescens Jack) leaves, Antioxidant Activity Test and Its Nanoemulsion Formulation |
| title_fullStr | Extraction of Sungkai (Peronema cannescens Jack) leaves, Antioxidant Activity Test and Its Nanoemulsion Formulation |
| title_full_unstemmed | Extraction of Sungkai (Peronema cannescens Jack) leaves, Antioxidant Activity Test and Its Nanoemulsion Formulation |
| title_short | Extraction of Sungkai (Peronema cannescens Jack) leaves, Antioxidant Activity Test and Its Nanoemulsion Formulation |
| title_sort | extraction of sungkai peronema cannescens jack leaves antioxidant activity test and its nanoemulsion formulation |
| url | https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/33/e3sconf_isac-iccme2023_07008.pdf |
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