Transcriptome sequencing reveals altered ciliogenesis under hypoxia in nasal epithelial cells from chronic rhinosinusitis with nasal polyps

Transcriptome sequencing reveals altered ciliogenesis under hypoxia in nasal epithelial cells from chronic rhinosinusitis with nasal polyps

Abstract Background Hypoxia is considered a key factor in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). However, the specific mechanism driving polypogenesis under hypoxic conditions is unclear. This study aimed to explore hypoxia‐induced alterations in the transcriptome of...

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Bibliographic Details
Main Authors: Jian Jiao, Puqi Hu, Mengyan Zhuang, Ying Li, Chao Cai, Xiangdong Wang, Luo Zhang
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Clinical and Translational Allergy
Subjects:
ciliogenesis
human nasal epithelial cells (HNECs)
hypoxia
transcriptome sequencing
Online Access:https://doi.org/10.1002/clt2.12168

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