Prediabetes screening: Questionable benefits in the golden years
Irrespective of the definition and diagnostic criteria used, the term prediabetes denotes a state of dysmetabolism with a high risk of progression to diabetes mellitus. Although diabetes-related complications may already be evident among individuals with prediabetes, interventions at this stage prim...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-06-01
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| Series: | Metabolism Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589936821000153 |
| _version_ | 1819014220653527040 |
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| author | Dimitrios Tsilingiris Natalia G. Vallianou Maria Dalamaga |
| author_facet | Dimitrios Tsilingiris Natalia G. Vallianou Maria Dalamaga |
| author_sort | Dimitrios Tsilingiris |
| collection | DOAJ |
| description | Irrespective of the definition and diagnostic criteria used, the term prediabetes denotes a state of dysmetabolism with a high risk of progression to diabetes mellitus. Although diabetes-related complications may already be evident among individuals with prediabetes, interventions at this stage primarily aim to hinder the development of overt hyperglycemia rather than to prevent complications. Current recommendations for prediabetes testing are common across all adult age categories. Recent evidence arising from the prospective investigation of the natural course of prediabetes among elderly individuals pose questions regarding the benefits of meticulous prediabetes screening in this age group. In view of this and due to the lack of sufficient data to concretely support a positive impact of further preventive strategies among older individuals, screening recommendations should be reevaluated to target selected elderly individuals who are most likely to benefit in terms of quality of life and prognosis. Further therapeutic measures should be tailored to the inherent features of this frail age group, in order to exert a meaningful effect on overall health status. |
| first_indexed | 2024-12-21T02:12:23Z |
| format | Article |
| id | doaj.art-cec17154a2b84402bcd9cf6e51e13bae |
| institution | Directory Open Access Journal |
| issn | 2589-9368 |
| language | English |
| last_indexed | 2024-12-21T02:12:23Z |
| publishDate | 2021-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Metabolism Open |
| spelling | doaj.art-cec17154a2b84402bcd9cf6e51e13bae2022-12-21T19:19:20ZengElsevierMetabolism Open2589-93682021-06-0110100091Prediabetes screening: Questionable benefits in the golden yearsDimitrios Tsilingiris0Natalia G. Vallianou1Maria Dalamaga2Corresponding author. Richard-Kuhn-Str. 1, 69123, Heidelberg, Germany.; First Department of Propaedeutic Internal Medicine, School of Medicine, National and Kapodistrian University of Athens, Laiko General Hospital, 17 St Thomas Street, 11527, Athens, GreeceFirst Department of Internal Medicine, Evangelismos General Hospital, 45-47 Ipsilantou Str, 10676, Athens, GreeceCorresponding author. Clinical Biochemistry, National and Kapodistrian University of Athens, Medical School, Mikras Asias #27, Goudi, 11527, Athens, Greece.; Department of Biological Chemistry, School of Medicine, National and Kapodistrian University of Athens, 75 Mikras Asias, 11527, Athens, GreeceIrrespective of the definition and diagnostic criteria used, the term prediabetes denotes a state of dysmetabolism with a high risk of progression to diabetes mellitus. Although diabetes-related complications may already be evident among individuals with prediabetes, interventions at this stage primarily aim to hinder the development of overt hyperglycemia rather than to prevent complications. Current recommendations for prediabetes testing are common across all adult age categories. Recent evidence arising from the prospective investigation of the natural course of prediabetes among elderly individuals pose questions regarding the benefits of meticulous prediabetes screening in this age group. In view of this and due to the lack of sufficient data to concretely support a positive impact of further preventive strategies among older individuals, screening recommendations should be reevaluated to target selected elderly individuals who are most likely to benefit in terms of quality of life and prognosis. Further therapeutic measures should be tailored to the inherent features of this frail age group, in order to exert a meaningful effect on overall health status.http://www.sciencedirect.com/science/article/pii/S2589936821000153DiabetesGlycated hemoglobinGlucosePrediabetesScreening |
| spellingShingle | Dimitrios Tsilingiris Natalia G. Vallianou Maria Dalamaga Prediabetes screening: Questionable benefits in the golden years Metabolism Open Diabetes Glycated hemoglobin Glucose Prediabetes Screening |
| title | Prediabetes screening: Questionable benefits in the golden years |
| title_full | Prediabetes screening: Questionable benefits in the golden years |
| title_fullStr | Prediabetes screening: Questionable benefits in the golden years |
| title_full_unstemmed | Prediabetes screening: Questionable benefits in the golden years |
| title_short | Prediabetes screening: Questionable benefits in the golden years |
| title_sort | prediabetes screening questionable benefits in the golden years |
| topic | Diabetes Glycated hemoglobin Glucose Prediabetes Screening |
| url | http://www.sciencedirect.com/science/article/pii/S2589936821000153 |
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