Topiramate causing type II renal tubular acidosis: A case and review of the mechanism

Abstract Topiramate has a wide array of pharmacologic effects, including proximal renal tubular acidosis (RTA). Clinicians must be wary of the possibility for development of somnolence due to compensatory hyperventilation and cardiac dysrhythmias.

Bibliographic Details
Main Authors: Michael Chahin, Monique Oye, Sonal Jadeja, Kimberly Sanders, Pramod Reddy
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.2733
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author Michael Chahin
Monique Oye
Sonal Jadeja
Kimberly Sanders
Pramod Reddy
author_facet Michael Chahin
Monique Oye
Sonal Jadeja
Kimberly Sanders
Pramod Reddy
author_sort Michael Chahin
collection DOAJ
description Abstract Topiramate has a wide array of pharmacologic effects, including proximal renal tubular acidosis (RTA). Clinicians must be wary of the possibility for development of somnolence due to compensatory hyperventilation and cardiac dysrhythmias.
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spelling doaj.art-cec1ecc595104f4e82995b339ec4607d2022-12-22T00:59:31ZengWileyClinical Case Reports2050-09042020-04-018473173310.1002/ccr3.2733Topiramate causing type II renal tubular acidosis: A case and review of the mechanismMichael Chahin0Monique Oye1Sonal Jadeja2Kimberly Sanders3Pramod Reddy4Department of Internal Medicine University of Florida College of Medicine ‐ Jacksonville Jacksonville FL USADepartment of Internal Medicine University of Florida College of Medicine ‐ Jacksonville Jacksonville FL USADepartment of Internal Medicine University of Florida College of Medicine ‐ Jacksonville Jacksonville FL USADepartment of Internal Medicine University of Florida College of Medicine ‐ Jacksonville Jacksonville FL USADepartment of Internal Medicine University of Florida College of Medicine ‐ Jacksonville Jacksonville FL USAAbstract Topiramate has a wide array of pharmacologic effects, including proximal renal tubular acidosis (RTA). Clinicians must be wary of the possibility for development of somnolence due to compensatory hyperventilation and cardiac dysrhythmias.https://doi.org/10.1002/ccr3.2733carbonic anhydrase inhibitorproximal renal tubular acidosistopiramate
spellingShingle Michael Chahin
Monique Oye
Sonal Jadeja
Kimberly Sanders
Pramod Reddy
Topiramate causing type II renal tubular acidosis: A case and review of the mechanism
Clinical Case Reports
carbonic anhydrase inhibitor
proximal renal tubular acidosis
topiramate
title Topiramate causing type II renal tubular acidosis: A case and review of the mechanism
title_full Topiramate causing type II renal tubular acidosis: A case and review of the mechanism
title_fullStr Topiramate causing type II renal tubular acidosis: A case and review of the mechanism
title_full_unstemmed Topiramate causing type II renal tubular acidosis: A case and review of the mechanism
title_short Topiramate causing type II renal tubular acidosis: A case and review of the mechanism
title_sort topiramate causing type ii renal tubular acidosis a case and review of the mechanism
topic carbonic anhydrase inhibitor
proximal renal tubular acidosis
topiramate
url https://doi.org/10.1002/ccr3.2733
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AT sonaljadeja topiramatecausingtypeiirenaltubularacidosisacaseandreviewofthemechanism
AT kimberlysanders topiramatecausingtypeiirenaltubularacidosisacaseandreviewofthemechanism
AT pramodreddy topiramatecausingtypeiirenaltubularacidosisacaseandreviewofthemechanism