EO-based mouthwashes: Is there something that should be known?

The possibility to utilize the antibacterial and antibiofilm potential of essential oils (EOs) in dentistry is recognized and best seen in the design of EO-based mouthwashes. The up-to-date results, obtained with the most commonly used formulation being consisted of thymol, eucalyptol, menthol, and...

Full description

Bibliographic Details
Main Authors: Marinković Jelena, Rakašević Dragana, Nemoda Milica, Nikolić Biljana, Marković Tatjana, Matijević Stevo, Marković Dejan
Format: Article
Language:English
Published: Balkan Stomatological Society 2023-01-01
Series:Balkan Journal of Dental Medicine
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/2335-0245/2023/2335-02452301032M.pdf
_version_ 1797853206984785920
author Marinković Jelena
Rakašević Dragana
Nemoda Milica
Nikolić Biljana
Marković Tatjana
Matijević Stevo
Marković Dejan
author_facet Marinković Jelena
Rakašević Dragana
Nemoda Milica
Nikolić Biljana
Marković Tatjana
Matijević Stevo
Marković Dejan
author_sort Marinković Jelena
collection DOAJ
description The possibility to utilize the antibacterial and antibiofilm potential of essential oils (EOs) in dentistry is recognized and best seen in the design of EO-based mouthwashes. The up-to-date results, obtained with the most commonly used formulation being consisted of thymol, eucalyptol, menthol, and methyl salicylate (Listerine), proved its efficacy against plaque and gingival inflammation. However, novel alcohol-free products remain to be further investigated. Commercially available mouthwash containing curcumin, clove oil, mentha oil, eucalyptol, thymol and tea tree oil, and the mouthwash based on ginger EO (a-zingiberene, b-bisabolene, b-sesquiphellandrene, curcumene), reduced plaque index and improved periodontal status of the patients. The plaque index was also reduced and overall healing was improved after the surgical removal of the third molar by mouthwash containing John wort oil. In addition, Cinnamomum zeylanicum EO-based mouthwash and mouthwash containing peppermint oil were efficient against stomatitis and xerostomia, respectively. In addition to beneficial effects achieved in the mouth, i.e. at the appropriate site of application, novel investigations pointed-out that EO-based mouthwashes could be recognized as efficient in the reduction of bacterial and viral aerosols. This has been shown for Listerine, and for several mouthwashes containing following active substances of plants' EO origin: a-farnesene, b-farnesene, farnesol, nerolidol, a-bulnesene, eremanthin, b-sesquiphellandrene, spiroether, cinnamylacetate, cinnamaldehyde, eugenol, menthol, and carvacrol. This finding could be of special interest, in order to be included in further clinical studies related to COVID -19 pandemic.
first_indexed 2024-04-09T19:46:53Z
format Article
id doaj.art-cec66f8ff9ec4a079217bff6211b5944
institution Directory Open Access Journal
issn 2335-0245
language English
last_indexed 2024-04-09T19:46:53Z
publishDate 2023-01-01
publisher Balkan Stomatological Society
record_format Article
series Balkan Journal of Dental Medicine
spelling doaj.art-cec66f8ff9ec4a079217bff6211b59442023-04-03T15:49:17ZengBalkan Stomatological SocietyBalkan Journal of Dental Medicine2335-02452023-01-0127132372335-02452301032MEO-based mouthwashes: Is there something that should be known?Marinković Jelena0Rakašević Dragana1Nemoda Milica2Nikolić Biljana3Marković Tatjana4https://orcid.org/0000-0003-1328-6223Matijević Stevo5Marković Dejan6https://orcid.org/0000-0002-4297-6744University of Belgrade, Institute of Nuclear Sciences - National Institute of the Republic of Serbia, Department of Physical Chemistry "VINČA" , Belgrade, SerbiaUniversity of Belgrade, School of Dental Medicine, Department of Oral Surgery, Belgrade, SerbiaUniversity of Belgrade, Faculty of Biology, Department of Microbiology, Belgrade, SerbiaInstitute for Medicinal Plant Research "dr Josif Pančić", Belgrade, SerbiaInstitute for Medicinal Plant Research "dr Josif Pančić", Belgrade, SerbiaUniversity of Defense, Faculty of Medicine of the Military Medical Academy, Clinic of Stomatology, Belgrade, SerbiaUniversity of Belgrade, School of Dental Medicine, Department of Paediatric Dentistry, Belgrade, SerbiaThe possibility to utilize the antibacterial and antibiofilm potential of essential oils (EOs) in dentistry is recognized and best seen in the design of EO-based mouthwashes. The up-to-date results, obtained with the most commonly used formulation being consisted of thymol, eucalyptol, menthol, and methyl salicylate (Listerine), proved its efficacy against plaque and gingival inflammation. However, novel alcohol-free products remain to be further investigated. Commercially available mouthwash containing curcumin, clove oil, mentha oil, eucalyptol, thymol and tea tree oil, and the mouthwash based on ginger EO (a-zingiberene, b-bisabolene, b-sesquiphellandrene, curcumene), reduced plaque index and improved periodontal status of the patients. The plaque index was also reduced and overall healing was improved after the surgical removal of the third molar by mouthwash containing John wort oil. In addition, Cinnamomum zeylanicum EO-based mouthwash and mouthwash containing peppermint oil were efficient against stomatitis and xerostomia, respectively. In addition to beneficial effects achieved in the mouth, i.e. at the appropriate site of application, novel investigations pointed-out that EO-based mouthwashes could be recognized as efficient in the reduction of bacterial and viral aerosols. This has been shown for Listerine, and for several mouthwashes containing following active substances of plants' EO origin: a-farnesene, b-farnesene, farnesol, nerolidol, a-bulnesene, eremanthin, b-sesquiphellandrene, spiroether, cinnamylacetate, cinnamaldehyde, eugenol, menthol, and carvacrol. This finding could be of special interest, in order to be included in further clinical studies related to COVID -19 pandemic.https://scindeks-clanci.ceon.rs/data/pdf/2335-0245/2023/2335-02452301032M.pdfcovid-19essential oilmouthwashperiodontal diseaseoral hygieneplaque
spellingShingle Marinković Jelena
Rakašević Dragana
Nemoda Milica
Nikolić Biljana
Marković Tatjana
Matijević Stevo
Marković Dejan
EO-based mouthwashes: Is there something that should be known?
Balkan Journal of Dental Medicine
covid-19
essential oil
mouthwash
periodontal disease
oral hygiene
plaque
title EO-based mouthwashes: Is there something that should be known?
title_full EO-based mouthwashes: Is there something that should be known?
title_fullStr EO-based mouthwashes: Is there something that should be known?
title_full_unstemmed EO-based mouthwashes: Is there something that should be known?
title_short EO-based mouthwashes: Is there something that should be known?
title_sort eo based mouthwashes is there something that should be known
topic covid-19
essential oil
mouthwash
periodontal disease
oral hygiene
plaque
url https://scindeks-clanci.ceon.rs/data/pdf/2335-0245/2023/2335-02452301032M.pdf
work_keys_str_mv AT marinkovicjelena eobasedmouthwashesistheresomethingthatshouldbeknown
AT rakasevicdragana eobasedmouthwashesistheresomethingthatshouldbeknown
AT nemodamilica eobasedmouthwashesistheresomethingthatshouldbeknown
AT nikolicbiljana eobasedmouthwashesistheresomethingthatshouldbeknown
AT markovictatjana eobasedmouthwashesistheresomethingthatshouldbeknown
AT matijevicstevo eobasedmouthwashesistheresomethingthatshouldbeknown
AT markovicdejan eobasedmouthwashesistheresomethingthatshouldbeknown