Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and review

We present a case of metastatic malignant melanoma to the urinary bladder diagnosed on a voided urinary cytology specimen in a patient who visited the emergency department complaining of right flank pain, and dark urine. The patient reported having previous episodes of kidney stones. Additionally, m...

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Main Authors: Joseph Alan Kagan, Susan Wu, Svetoslav Bardarov
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Cytology
Subjects:
Online Access:http://www.jcytol.org/article.asp?issn=0970-9371;year=2017;volume=34;issue=2;spage=101;epage=103;aulast=Kagan
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author Joseph Alan Kagan
Susan Wu
Svetoslav Bardarov
author_facet Joseph Alan Kagan
Susan Wu
Svetoslav Bardarov
author_sort Joseph Alan Kagan
collection DOAJ
description We present a case of metastatic malignant melanoma to the urinary bladder diagnosed on a voided urinary cytology specimen in a patient who visited the emergency department complaining of right flank pain, and dark urine. The patient reported having previous episodes of kidney stones. Additionally, more detailed clinical history obtained after the cytological diagnosis, revealed a previous excision of malignant melanoma on the back 10 years ago. The diagnosis of metastatic malignant melanoma was based solely on voided urine cytology. While metastases of malignant melanoma to urinary bladder are well known, the significance of pigmented cells in voided urine specimens is not well documented. In this article we provide a discussion as well as a review of the literature about possible disease entities associated with pigment containing urothelial as well as non-urothelial cells.
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spelling doaj.art-ceccb73da01a425f89e2801038b181a32022-12-22T03:12:06ZengWolters Kluwer Medknow PublicationsJournal of Cytology0970-93712017-01-0134210110310.4103/0970-9371.203578Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and reviewJoseph Alan KaganSusan WuSvetoslav BardarovWe present a case of metastatic malignant melanoma to the urinary bladder diagnosed on a voided urinary cytology specimen in a patient who visited the emergency department complaining of right flank pain, and dark urine. The patient reported having previous episodes of kidney stones. Additionally, more detailed clinical history obtained after the cytological diagnosis, revealed a previous excision of malignant melanoma on the back 10 years ago. The diagnosis of metastatic malignant melanoma was based solely on voided urine cytology. While metastases of malignant melanoma to urinary bladder are well known, the significance of pigmented cells in voided urine specimens is not well documented. In this article we provide a discussion as well as a review of the literature about possible disease entities associated with pigment containing urothelial as well as non-urothelial cells.http://www.jcytol.org/article.asp?issn=0970-9371;year=2017;volume=34;issue=2;spage=101;epage=103;aulast=KaganHemosiderosis; melanoma; urothelial cells
spellingShingle Joseph Alan Kagan
Susan Wu
Svetoslav Bardarov
Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and review
Journal of Cytology
Hemosiderosis; melanoma; urothelial cells
title Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and review
title_full Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and review
title_fullStr Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and review
title_full_unstemmed Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and review
title_short Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and review
title_sort significance of pigmented urothelial and non urothelial cells in voided urine specimens a case report and review
topic Hemosiderosis; melanoma; urothelial cells
url http://www.jcytol.org/article.asp?issn=0970-9371;year=2017;volume=34;issue=2;spage=101;epage=103;aulast=Kagan
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AT susanwu significanceofpigmentedurothelialandnonurothelialcellsinvoidedurinespecimensacasereportandreview
AT svetoslavbardarov significanceofpigmentedurothelialandnonurothelialcellsinvoidedurinespecimensacasereportandreview