Short‐Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older Adults
Abstract Extensive evidence suggests that ambient air pollution contributes to a higher risk of hospital admissions for cerebrovascular diseases; however, its association with admissions for sequelae of stroke remains unclear. A time‐stratified case‐crossover study was conducted among 31,810 older a...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Geophysical Union (AGU)
2022-11-01
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| Series: | GeoHealth |
| Subjects: | |
| Online Access: | https://doi.org/10.1029/2022GH000700 |
| _version_ | 1797946321117642752 |
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| author | Rui Wang Ruijun Xu Jing Wei Tingting Liu Yunshao Ye Yingxin Li Qiaoxuan Lin Yun Zhou Suli Huang Ziquan Lv Qi Tian Yuewei Liu |
| author_facet | Rui Wang Ruijun Xu Jing Wei Tingting Liu Yunshao Ye Yingxin Li Qiaoxuan Lin Yun Zhou Suli Huang Ziquan Lv Qi Tian Yuewei Liu |
| author_sort | Rui Wang |
| collection | DOAJ |
| description | Abstract Extensive evidence suggests that ambient air pollution contributes to a higher risk of hospital admissions for cerebrovascular diseases; however, its association with admissions for sequelae of stroke remains unclear. A time‐stratified case‐crossover study was conducted among 31,810 older adults who were admitted to hospital for sequelae of stroke in Guangzhou, China during 2016–2019. For each subject, daily residential exposure to fine particulate matter (PM2.5), inhalable particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3) was extracted from a validated grid data set. Conditional logistic regression models were used for exposure‐response analyses. In single‐pollutant models, each interquartile range (IQR) increase of lag 04‐day exposure to CO (IQR: 0.25 mg/m3) and lag 3‐day exposure to O3 (69.6 μg/m3) was significantly associated with a 4.53% (95% confidence interval: 1.67%, 7.47%) and 5.63% (1.92%, 9.48%) increase in odds of hospital admissions for sequelae of stroke, respectively. These associations did not significantly vary across age or sex. With further adjustment for each of the other pollutants in 2‐pollutant models, the association for CO did not change significantly, while the association for O3 disappeared. We estimated that 7.72% of the hospital admissions were attributable to CO exposures. No significant or consistent association was observed for exposure to PM2.5, PM10, SO2, or NO2. In conclusion, short‐term exposure to ambient CO, even at levels below the WHO air quality guideline, was significantly associated with an increased odds of hospital admissions for sequelae of stroke, which may lead to considerable excess hospital admissions. |
| first_indexed | 2024-04-10T21:09:10Z |
| format | Article |
| id | doaj.art-cecd940c641849a180b434babb1f7f64 |
| institution | Directory Open Access Journal |
| issn | 2471-1403 |
| language | English |
| last_indexed | 2024-04-10T21:09:10Z |
| publishDate | 2022-11-01 |
| publisher | American Geophysical Union (AGU) |
| record_format | Article |
| series | GeoHealth |
| spelling | doaj.art-cecd940c641849a180b434babb1f7f642023-01-21T08:51:48ZengAmerican Geophysical Union (AGU)GeoHealth2471-14032022-11-01611n/an/a10.1029/2022GH000700Short‐Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older AdultsRui Wang0Ruijun Xu1Jing Wei2Tingting Liu3Yunshao Ye4Yingxin Li5Qiaoxuan Lin6Yun Zhou7Suli Huang8Ziquan Lv9Qi Tian10Yuewei Liu11Luohu District Chronic Disease Hospital Shenzhen ChinaDepartment of Epidemiology School of Public Health Sun Yat‐sen University Guangzhou ChinaDepartment of Atmospheric and Oceanic Science Earth System Science Interdisciplinary Center University of Maryland College Park MD USADepartment of Epidemiology School of Public Health Sun Yat‐sen University Guangzhou ChinaGuangzhou Health Technology Identification & Human Resources Assessment Center Guangzhou ChinaDepartment of Epidemiology School of Public Health Sun Yat‐sen University Guangzhou ChinaGuangzhou Health Technology Identification & Human Resources Assessment Center Guangzhou ChinaDepartment of Preventive Medicine School of Public Health Guangzhou Medical University Guangzhou ChinaDepartment of Environment and Health Shenzhen Center for Disease Control and Prevention Shenzhen ChinaDepartment of Molecular Epidemiology Shenzhen Center for Disease Control and Prevention Shenzhen ChinaGuangzhou Health Technology Identification & Human Resources Assessment Center Guangzhou ChinaDepartment of Epidemiology School of Public Health Sun Yat‐sen University Guangzhou ChinaAbstract Extensive evidence suggests that ambient air pollution contributes to a higher risk of hospital admissions for cerebrovascular diseases; however, its association with admissions for sequelae of stroke remains unclear. A time‐stratified case‐crossover study was conducted among 31,810 older adults who were admitted to hospital for sequelae of stroke in Guangzhou, China during 2016–2019. For each subject, daily residential exposure to fine particulate matter (PM2.5), inhalable particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3) was extracted from a validated grid data set. Conditional logistic regression models were used for exposure‐response analyses. In single‐pollutant models, each interquartile range (IQR) increase of lag 04‐day exposure to CO (IQR: 0.25 mg/m3) and lag 3‐day exposure to O3 (69.6 μg/m3) was significantly associated with a 4.53% (95% confidence interval: 1.67%, 7.47%) and 5.63% (1.92%, 9.48%) increase in odds of hospital admissions for sequelae of stroke, respectively. These associations did not significantly vary across age or sex. With further adjustment for each of the other pollutants in 2‐pollutant models, the association for CO did not change significantly, while the association for O3 disappeared. We estimated that 7.72% of the hospital admissions were attributable to CO exposures. No significant or consistent association was observed for exposure to PM2.5, PM10, SO2, or NO2. In conclusion, short‐term exposure to ambient CO, even at levels below the WHO air quality guideline, was significantly associated with an increased odds of hospital admissions for sequelae of stroke, which may lead to considerable excess hospital admissions.https://doi.org/10.1029/2022GH000700air pollutioncarbon monoxidesequelae of strokehospital admissioncase‐crossover study |
| spellingShingle | Rui Wang Ruijun Xu Jing Wei Tingting Liu Yunshao Ye Yingxin Li Qiaoxuan Lin Yun Zhou Suli Huang Ziquan Lv Qi Tian Yuewei Liu Short‐Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older Adults GeoHealth air pollution carbon monoxide sequelae of stroke hospital admission case‐crossover study |
| title | Short‐Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older Adults |
| title_full | Short‐Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older Adults |
| title_fullStr | Short‐Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older Adults |
| title_full_unstemmed | Short‐Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older Adults |
| title_short | Short‐Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older Adults |
| title_sort | short term exposure to ambient air pollution and hospital admissions for sequelae of stroke in chinese older adults |
| topic | air pollution carbon monoxide sequelae of stroke hospital admission case‐crossover study |
| url | https://doi.org/10.1029/2022GH000700 |
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