Procyanidin C1 Activates the Nrf2/HO-1 Signaling Pathway to Prevent Glutamate-Induced Apoptotic HT22 Cell Death

Procyanidin C1 Activates the Nrf2/HO-1 Signaling Pathway to Prevent Glutamate-Induced Apoptotic HT22 Cell Death

Natural sources are very promising materials for the discovery of novel bioactive compounds with diverse pharmacological effects. In recent years, many researchers have focused on natural sources as a means to prevent neuronal cell death in neuropathological conditions. This study focused on identif...

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Bibliographic Details
Main Authors: Ji Hoon Song, Hae-Jeung Lee, Ki Sung Kang
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
procyanidin C1
glutamate
oxidative stress
Nrf2/HO-1 signaling pathway
MAPK
neuroprotective effects
Online Access:http://www.mdpi.com/1422-0067/20/1/142

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