Thermostable chaperone-based polypeptide biosynthesis: Enfuvirtide model product quality and protocol-related impurities

Large peptide biosynthesis is a valuable alternative to conventional chemical synthesis. Enfuvirtide, the largest therapeutic peptide used in HIV infection treatment, was synthesized in our thermostable chaperone-based peptide biosynthesis system and evaluated for peptide quality as well as the prof...

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Bibliografiska uppgifter
Huvudupphovsmän: Vladimir Zenin, Andrey Tsedilin, Maria Yurkova, Andrey Siniavin, Alexey Fedorov
Materialtyp: Artikel
Språk:English
Publicerad: Public Library of Science (PLoS) 2023-01-01
Serie:PLoS ONE
Länkar:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249821/?tool=EBI