FOX-A1 contributes to acquisition of chemoresistance in human lung adenocarcinoma via transactivation of SOX5Research in context

FOX-A1 contributes to acquisition of chemoresistance in human lung adenocarcinoma via transactivation of SOX5Research in context

Background: Chemoresistance is a major obstacle for the effective treatment of lung adenocarcinoma (LAD). Forkhead box (FOX) proteins have been demonstrated to play critical roles in promoting epithelial-mesenchymal transition (EMT) and chemoresistance. However, whether FOX proteins contribute to th...

Full description

Bibliographic Details
Main Authors:	Dongqin Chen, Rui Wang, Chen Yu, Fei Cao, Xuefeng Zhang, Feng Yan, Longbang Chen, Hong Zhu, Zhengyuan Yu, Jifeng Feng
Format:	Article
Language:	English
Published:	Elsevier 2019-06-01
Series:	EBioMedicine
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396419303548

Similar Items

Notch-1 Confers Chemoresistance in Lung Adenocarcinoma to Taxanes through AP-1/microRNA-451 Mediated Regulation of MDR-1
by: Jiayuan Huang, et al.
Published: (2016-01-01)

TFAP2C-Activated MALAT1 Modulates the Chemoresistance of Docetaxel-Resistant Lung Adenocarcinoma Cells
by: Jing Chen, et al.
Published: (2019-03-01)

MARCKSL1–2 reverses docetaxel-resistance of lung adenocarcinoma cells by recruiting SUZ12 to suppress HDAC1 and elevate miR-200b
by: Min Jiang, et al.
Published: (2022-07-01)

Dimerization and Transactivation Domains as Candidates for Functional Modulation and Diversity of Sox9.
by: Marcos Tadeu Geraldo, et al.
Published: (2016-01-01)

SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination.
by: Sayaka Fujiwara, et al.
Published: (2014-01-01)

Sox transcription factors require selective interactions with Oct4 and specific transactivation functions to mediate reprogramming
by: Aksoy, Irene, et al.
Published: (2014)

Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence
by: Aldwin Suryo Rahmanto, et al.
Published: (2017-01-01)

Andrographolide Induces Noxa-Dependent Apoptosis by Transactivating ATF4 in Human Lung Adenocarcinoma Cells
by: Junqian Zhang, et al.
Published: (2021-04-01)

The role of miRNAs in the diagnosis, chemoresistance, and prognosis of pancreatic ductal adenocarcinoma
by: Ren L, et al.
Published: (2018-01-01)

A novel lncRNA SOX2OT promotes the malignancy of human colorectal cancer by interacting with miR-194-5p/SOX5 axis
by: Ye Feng, et al.
Published: (2021-05-01)

Potential Role of miRNAs in the Acquisition of Chemoresistance in Neuroblastoma
by: Barbara Marengo, et al.
Published: (2021-02-01)

SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression.
by: Victor Y L Leung, et al.
Published: (2011-11-01)

Structure of the EGF receptor transactivation circuit integrates with cell context
by: Joslin, Elizabeth J., et al.
Published: (2012)

Metabolic Reprogramming of Chemoresistant Cancer Cells and the Potential Significance of Metabolic Regulation in the Reversal of Cancer Chemoresistance
by: Xun Chen, et al.
Published: (2020-07-01)

Constitutive activation of Notch2 signalling confers chemoresistance to neural stem cells via transactivation of fibroblast growth factor receptor-1
by: Mercedes Tomé, et al.
Published: (2019-03-01)

Case report: A de novo Non-sense SOX9 mutation (p.Q417*) located in transactivation domain is Responsible for Campomelic Dysplasia
by: Xingxing Qiao, et al.
Published: (2023-01-01)

Girdin Promotes Tumorigenesis and Chemoresistance in Lung Adenocarcinoma by Interacting with PKM2
by: Fuyang Cao, et al.
Published: (2022-11-01)

Prognostic significance of SOX2 for chemotherapeutic patients with oral squamous cell carcinoma
by: Xuefeng Zhang, et al.
Published: (2024-04-01)

SOX11/PRDX2 axis modulates redox homeostasis and chemoresistance in aggressive mantle cell lymphoma
by: Anna De Bolòs, et al.
Published: (2024-04-01)

Self-restricted circular RNA circSOX2 suppressed the malignant progression in SOX2-amplified LUSC
by: Yingkuan Liang, et al.
Published: (2022-10-01)

Dichotomous transactivation domains contribute to growth inhibitory and promotion functions of TAp73
by: Li, Dan, et al.
Published: (2024)

The Underlying Mechanisms of Noncoding RNAs in the Chemoresistance of Hepatocellular Carcinoma
by: Man Wang, et al.
Published: (2020-09-01)

Identification of miRNAs contributing to neuroblastoma chemoresistance
by: Duncan Ayers, et al.
Published: (2015-01-01)

Plasma Exosomal miRNA Expression Profile as Oxaliplatin-Based Chemoresistant Biomarkers in Colorectal Adenocarcinoma
by: Jiayi Han, et al.
Published: (2020-09-01)

Pancreatic ductal adenocarcinoma chemoresistance: From metabolism reprogramming to novel treatment
by: Jingcheng Zhang, et al.
Published: (2024-02-01)

VPS33B suppresses lung adenocarcinoma metastasis and chemoresistance to cisplatin
by: Zhen Liu, et al.
Published: (2021-05-01)

Cellular RelB interacts with the transactivator Tat and enhance HIV-1 expression
by: Meng Wang, et al.
Published: (2018-09-01)

Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production.
by: Claudia R Oliva, et al.
Published: (2011-01-01)

Hypoxia-inducible factor-1α regulates chemotactic migration of pancreatic ductal adenocarcinoma cells through directly transactivating the CX3CR1 gene.
by: Tiansuo Zhao, et al.
Published: (2012-01-01)

SOX9 promotes the invasion and migration of lung adenocarcinoma cells by activating the RAP1 signaling pathway
by: Jun-fa Yang, et al.
Published: (2023-11-01)

Hepatic stellate cells secreted hepatocyte growth factor contributes to the chemoresistance of hepatocellular carcinoma.
by: Guofeng Yu, et al.
Published: (2013-01-01)

FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2.
by: Yeri Lee, et al.
Published: (2015-01-01)

MicroRNA-320d regulates tumor growth and invasion by promoting FoxM1 and predicts poor outcome in gastric cardiac adenocarcinoma
by: Xiaojie Chen, et al.
Published: (2020-06-01)

IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma
by: Xuehua Zhang, et al.
Published: (2023-05-01)

Lauric Acid Overcomes Hypoxia-Induced Gemcitabine Chemoresistance in Pancreatic Ductal Adenocarcinoma
by: Tadataka Takagi, et al.
Published: (2023-04-01)

Epithelial to Mesenchymal Transition: Key Regulator of Pancreatic Ductal Adenocarcinoma Progression and Chemoresistance
by: Kostas Palamaris, et al.
Published: (2021-11-01)

HB-EGF, Transactivation, and Cardiac Hypertrophy
by: Seiji Takashima, et al.
Published: (2007-03-01)

The Fox genes of Branchiostoma floridae.
by: Yu, J, et al.
Published: (2008)

The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment
by: Matthias Parrini, et al.
Published: (2018-12-01)

SOX15 Governs Transcription in Human Stratified Epithelia and a Subset of Esophageal AdenocarcinomasSummary
by: Rita Sulahian, et al.
Published: (2015-11-01)