At short telomeres Tel1 directs early replication and phosphorylates Rif1.
The replication time of Saccharomyces cerevisiae telomeres responds to TG1-3 repeat length, with telomeres of normal length replicating late during S phase and short telomeres replicating early. Here we show that Tel1 kinase, which is recruited to short telomeres, specifies their early replication,...
Autors principals: | Akila Sridhar, Sylwia Kedziora, Anne D Donaldson |
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Format: | Article |
Idioma: | English |
Publicat: |
Public Library of Science (PLoS)
2014-10-01
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Col·lecció: | PLoS Genetics |
Accés en línia: | http://europepmc.org/articles/PMC4199499?pdf=render |
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