At short telomeres Tel1 directs early replication and phosphorylates Rif1.

The replication time of Saccharomyces cerevisiae telomeres responds to TG1-3 repeat length, with telomeres of normal length replicating late during S phase and short telomeres replicating early. Here we show that Tel1 kinase, which is recruited to short telomeres, specifies their early replication,...

Descripció completa

Dades bibliogràfiques
Autors principals: Akila Sridhar, Sylwia Kedziora, Anne D Donaldson
Format: Article
Idioma:English
Publicat: Public Library of Science (PLoS) 2014-10-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC4199499?pdf=render

Ítems similars