At short telomeres Tel1 directs early replication and phosphorylates Rif1.
The replication time of Saccharomyces cerevisiae telomeres responds to TG1-3 repeat length, with telomeres of normal length replicating late during S phase and short telomeres replicating early. Here we show that Tel1 kinase, which is recruited to short telomeres, specifies their early replication,...
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artikkeli |
| Kieli: | English |
| Julkaistu: |
Public Library of Science (PLoS)
2014-10-01
|
| Sarja: | PLoS Genetics |
| Linkit: | http://europepmc.org/articles/PMC4199499?pdf=render |