At short telomeres Tel1 directs early replication and phosphorylates Rif1.
The replication time of Saccharomyces cerevisiae telomeres responds to TG1-3 repeat length, with telomeres of normal length replicating late during S phase and short telomeres replicating early. Here we show that Tel1 kinase, which is recruited to short telomeres, specifies their early replication,...
| Main Authors: | , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Public Library of Science (PLoS)
2014-10-01
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| 叢編: | PLoS Genetics |
| 在線閱讀: | http://europepmc.org/articles/PMC4199499?pdf=render |