Repair and DNA Polymerase Bypass of Clickable Pyrimidine Nucleotides

Repair and DNA Polymerase Bypass of Clickable Pyrimidine Nucleotides

Clickable nucleosides, most often 5-ethynyl-2′-deoxyuridine (EtU), are widely used in studies of DNA replication in living cells and in DNA functionalization for bionanotechology applications. Although clickable dNTPs are easily incorporated by DNA polymerases into the growing chain, afterwards they...

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Bibliografiske detaljer
Main Authors: Anton V. Endutkin, Anna V. Yudkina, Timofey D. Zharkov, Alexander E. Barmatov, Daria V. Petrova, Daria V. Kim, Dmitry O. Zharkov
Format: Article
Sprog:English
Udgivet: MDPI AG 2024-06-01
Serier:Biomolecules
Fag:
click chemistry
metabolic labeling
DNA repair
replication
DNA glycosylases
DNA polymerases
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