Therapeutic effect of one-time root canal treatment for irreversible pulpitis

Objective To compare the therapeutic effects of one-time root canal treatment versus two-time treatment in patients with irreversible pulpitis. Methods We classified 130 patients into a one-time treatment group (group A; n = 68) and a two-time treatment group (group B; n = 62) according to the numbe...

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Main Authors: Yu Lu, Zhongjun Liu, Jinyu Huang, Chengxia Liu
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060519879287
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author Yu Lu
Zhongjun Liu
Jinyu Huang
Chengxia Liu
author_facet Yu Lu
Zhongjun Liu
Jinyu Huang
Chengxia Liu
author_sort Yu Lu
collection DOAJ
description Objective To compare the therapeutic effects of one-time root canal treatment versus two-time treatment in patients with irreversible pulpitis. Methods We classified 130 patients into a one-time treatment group (group A; n = 68) and a two-time treatment group (group B; n = 62) according to the number of patient visits. Clinical efficacy at 6 months and 1 year follow-ups as well as serum levels of interleukin-6, tumor necrosis factor alpha, and high-sensitivity C-reactive protein before and 1 week after endodontic treatment were observed. Additionally, the level of treatment satisfaction between the two groups was compared, and the degree of pain was evaluated using the visual analogue scale. Result One week after treatment, serum interleukin-6, tumor necrosis factor alpha, and high-sensitivity C-reactive protein levels were significantly decreased in the two groups; however, levels in group B were significantly lower than those in group A. Additionally, visual analogue scale scores of patients in group A were significantly higher than those of patients in group B. Conclusion One-time root canal therapy can effectively improve postoperative pain and the expression of inflammatory factors in the serum of patients undergoing treatment.
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spelling doaj.art-cedd37bbcffb42fc834d51c960592d922022-12-21T19:58:45ZengSAGE PublishingJournal of International Medical Research1473-23002020-10-014810.1177/0300060519879287Therapeutic effect of one-time root canal treatment for irreversible pulpitisYu LuZhongjun LiuJinyu HuangChengxia LiuObjective To compare the therapeutic effects of one-time root canal treatment versus two-time treatment in patients with irreversible pulpitis. Methods We classified 130 patients into a one-time treatment group (group A; n = 68) and a two-time treatment group (group B; n = 62) according to the number of patient visits. Clinical efficacy at 6 months and 1 year follow-ups as well as serum levels of interleukin-6, tumor necrosis factor alpha, and high-sensitivity C-reactive protein before and 1 week after endodontic treatment were observed. Additionally, the level of treatment satisfaction between the two groups was compared, and the degree of pain was evaluated using the visual analogue scale. Result One week after treatment, serum interleukin-6, tumor necrosis factor alpha, and high-sensitivity C-reactive protein levels were significantly decreased in the two groups; however, levels in group B were significantly lower than those in group A. Additionally, visual analogue scale scores of patients in group A were significantly higher than those of patients in group B. Conclusion One-time root canal therapy can effectively improve postoperative pain and the expression of inflammatory factors in the serum of patients undergoing treatment.https://doi.org/10.1177/0300060519879287
spellingShingle Yu Lu
Zhongjun Liu
Jinyu Huang
Chengxia Liu
Therapeutic effect of one-time root canal treatment for irreversible pulpitis
Journal of International Medical Research
title Therapeutic effect of one-time root canal treatment for irreversible pulpitis
title_full Therapeutic effect of one-time root canal treatment for irreversible pulpitis
title_fullStr Therapeutic effect of one-time root canal treatment for irreversible pulpitis
title_full_unstemmed Therapeutic effect of one-time root canal treatment for irreversible pulpitis
title_short Therapeutic effect of one-time root canal treatment for irreversible pulpitis
title_sort therapeutic effect of one time root canal treatment for irreversible pulpitis
url https://doi.org/10.1177/0300060519879287
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