<i>Hypericum</i> spp.—An Overview of the Extraction Methods and Analysis of Compounds

The <i>Hypericum</i> genus contains one of the few genera of flowering plants that contains a species with authorization for marketing as a traditional medicine, <i>H. perforatum</i>. Due to the fact that this is a large genus, comprising numerous species, a large amount of i...

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Bibliographic Details
Main Authors: Valentin Ion, Irina Ielciu, Anca-Gabriela Cârje, Daniela Lucia Muntean, Gianina Crişan, Ramona Păltinean
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Separations
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Online Access:https://www.mdpi.com/2297-8739/9/1/17
Description
Summary:The <i>Hypericum</i> genus contains one of the few genera of flowering plants that contains a species with authorization for marketing as a traditional medicine, <i>H. perforatum</i>. Due to the fact that this is a large genus, comprising numerous species, a large amount of interest has been shown over the years in the study of its various pharmacological activities. The chemical composition of these species is quite similar, containing compounds belonging to the class of phloroglucinol derivatives, naphthodianthrones, phenols, flavonoids and essential oils. Taking all of this into consideration, the present study aims to offer an overview of the species of the genus from the point of view of their extraction techniques and analysis methods. An extensive study on the scientific literature was performed, and it revealed a wide range of solvents and extraction methods, among which ethanol and methanol, together with maceration and ultrasonication, are the most frequent. Regarding analysis methods, separation and spectral techniques are the most employed. Therefore, the present study provides necessary data for future studies on the species of the genus, offering a complete overview and a possible basis for their development.
ISSN:2297-8739