Treatment of diabetes mellitus-associated neuropathy with vitamin E and Eve primrose
Background: The aim of this report was to assess the efficacy and safety of a combination of vitamin E, an antioxidant, and Eve Primrose in the management of painful diabetes mellitus (DM) neuropathy. Materials and Methods: This was an interventional study that evaluated the efficacy and safety of a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2014;volume=18;issue=6;spage=846;epage=849;aulast=Ogbera |
| _version_ | 1817976211973865472 |
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| author | Anthonia Okeoghene Ogbera Emmanuel Ezeobi Chioma Unachukwu Olajumoke Oshinaike |
| author_facet | Anthonia Okeoghene Ogbera Emmanuel Ezeobi Chioma Unachukwu Olajumoke Oshinaike |
| author_sort | Anthonia Okeoghene Ogbera |
| collection | DOAJ |
| description | Background: The aim of this report was to assess the efficacy and safety of a combination of vitamin E, an antioxidant, and Eve Primrose in the management of painful diabetes mellitus (DM) neuropathy. Materials and Methods: This was an interventional study that evaluated the efficacy and safety of a combination of vitamin E and Eve Primrose in the management of DM neuropathy. The study was conducted at the Diabetic Centre of the Lagos State University Teaching Hospital, Ikeja. Eighty individuals with type 2 DM who had painful neuropathy were recruited for this study, which took place for a duration of 1 year. The study subjects underwent clinical and biochemical assessment at baseline and were given vitamin E in a dose of 400 mg in combination with Eve Primrose in doses ranging 500-1000 mg/day. They were afterward assessed for relief of symptoms and possible untoward effects after 2 weeks and, thereafter, monthly for 3 months. The main outcome measure was amelioration of symptoms of neuropathy . Results: The mean age and age range of the study subjects were 58.2 years and 37-70 years, respectively. A total of 70 patients (88%) of the study population reported relief from neuropathic pains. Clinical parameters were comparable between the responders and non-responders. One characteristic feature of the non-responders was that they all had vibration perception threshold of ≥25 mV, which was indicative of severe neuropathy. Conclusion: The combination of vitamin E and Eve Primrose is beneficial in the management of mild to moderate diabetic neuropathy. |
| first_indexed | 2024-04-13T22:00:29Z |
| format | Article |
| id | doaj.art-cee6bb23ea5b46228cd730c7f4da150d |
| institution | Directory Open Access Journal |
| issn | 2230-8210 2230-9500 |
| language | English |
| last_indexed | 2024-04-13T22:00:29Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-cee6bb23ea5b46228cd730c7f4da150d2022-12-22T02:28:07ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002014-01-0118684684910.4103/2230-8210.140270Treatment of diabetes mellitus-associated neuropathy with vitamin E and Eve primroseAnthonia Okeoghene OgberaEmmanuel EzeobiChioma UnachukwuOlajumoke OshinaikeBackground: The aim of this report was to assess the efficacy and safety of a combination of vitamin E, an antioxidant, and Eve Primrose in the management of painful diabetes mellitus (DM) neuropathy. Materials and Methods: This was an interventional study that evaluated the efficacy and safety of a combination of vitamin E and Eve Primrose in the management of DM neuropathy. The study was conducted at the Diabetic Centre of the Lagos State University Teaching Hospital, Ikeja. Eighty individuals with type 2 DM who had painful neuropathy were recruited for this study, which took place for a duration of 1 year. The study subjects underwent clinical and biochemical assessment at baseline and were given vitamin E in a dose of 400 mg in combination with Eve Primrose in doses ranging 500-1000 mg/day. They were afterward assessed for relief of symptoms and possible untoward effects after 2 weeks and, thereafter, monthly for 3 months. The main outcome measure was amelioration of symptoms of neuropathy . Results: The mean age and age range of the study subjects were 58.2 years and 37-70 years, respectively. A total of 70 patients (88%) of the study population reported relief from neuropathic pains. Clinical parameters were comparable between the responders and non-responders. One characteristic feature of the non-responders was that they all had vibration perception threshold of ≥25 mV, which was indicative of severe neuropathy. Conclusion: The combination of vitamin E and Eve Primrose is beneficial in the management of mild to moderate diabetic neuropathy.http://www.ijem.in/article.asp?issn=2230-8210;year=2014;volume=18;issue=6;spage=846;epage=849;aulast=OgberaDiabetes mellitusEve Primroseneuropathyvitamin E |
| spellingShingle | Anthonia Okeoghene Ogbera Emmanuel Ezeobi Chioma Unachukwu Olajumoke Oshinaike Treatment of diabetes mellitus-associated neuropathy with vitamin E and Eve primrose Indian Journal of Endocrinology and Metabolism Diabetes mellitus Eve Primrose neuropathy vitamin E |
| title | Treatment of diabetes mellitus-associated neuropathy with vitamin E and Eve primrose |
| title_full | Treatment of diabetes mellitus-associated neuropathy with vitamin E and Eve primrose |
| title_fullStr | Treatment of diabetes mellitus-associated neuropathy with vitamin E and Eve primrose |
| title_full_unstemmed | Treatment of diabetes mellitus-associated neuropathy with vitamin E and Eve primrose |
| title_short | Treatment of diabetes mellitus-associated neuropathy with vitamin E and Eve primrose |
| title_sort | treatment of diabetes mellitus associated neuropathy with vitamin e and eve primrose |
| topic | Diabetes mellitus Eve Primrose neuropathy vitamin E |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2014;volume=18;issue=6;spage=846;epage=849;aulast=Ogbera |
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